Results 101 to 110 of about 54,026 (308)

New hints on nutrients dynamics and their impact on carbon sequestration in the Mediterranean Sea

open access: yes, 2009
In the World Ocean nitrogen and phosphorus cycles are deeply linked to the carbon cycle. As nitrate and phosphate play an important role in controlling biological production, the intensity of atmospheric carbon sequestration is strongly influenced by ...
Ibello, Valeria
core  

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Dating the cyanobacterial ancestor of the chloroplast

open access: yes, 2009
Cyanobacteria have played a pivotal role in the history of life on Earth being the first organism to carry out oxygenic photosynthesis, which changed atmospheric chemistry and allowed the evolution of Eukarya.
Luisa Falcon   +2 more
core  

The physiological-ecology of the cyanobacterium Microcoleus [PDF]

open access: yes, 1989
A study was carried out to determine how widespread N(_2) fixation is in the cyanobacterium Microcoleus, both in the laboratory and in the field. The research was extended to compare the influence of environmental variables on both Ng fixing and non ...
Davies, Gail
core  

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

open access: yesAdvanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska   +14 more
wiley   +1 more source

A Molecular-Level Mechanism of the Biological N2 Fixation

open access: yes, 2019
We present a detailed molecular-level mechanism for the biological fixation of atmospheric nitrogen into ammonia. The mechanism is based on a series of electronic structure calculations and provides insight into the key question of what it is that the ...
Vanessa Jane, Bukas   +1 more
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

open access: yesAdvanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao   +12 more
wiley   +1 more source

Bacterial N2-fixation in mangrove ecosystems: insights from a diazotroph-mangrove interaction

open access: yesFrontiers in Microbiology, 2015
Mangrove forests are highly productive ecosystems but represent low nutrient environments. Nitrogen availability is one of the main factors limiting mangrove growth.
Gabriela eAlfaro-Espinoza   +1 more
doaj   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

open access: yesAdvanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma   +11 more
wiley   +1 more source

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