Results 241 to 250 of about 7,264,527 (287)

Nota introduttiva n. 13 – aprile 2013

open access: yesDiacronie. Studi di Storia Contemporanea, 2013
Elisa Grandi, Giovanni Venegoni
doaj  

Understanding Surgery Refusal in Patients with Colorectal Liver Metastases. [PDF]

open access: yesJ Gastrointest Cancer
Andreasen LW   +4 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Editoriale n.13

open access: yes, 2002
CALVANI, ANTONIO, BONAIUTI, GIOVANNI
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Sufí 2007, n. 13 [PDF]

open access: yes, 2007
Centro Sufí Nematollāhi
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Emotion regulation in prolonged grief disorder in later life: Protocol and rationale for a longitudinal neuroimaging study. [PDF]

open access: yesImaging Neurosci (Camb)
Hwang G   +10 more
europepmc   +1 more source

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