Nota introduttiva n. 13 – aprile 2013
Elisa Grandi, Giovanni Venegoni
doaj
Understanding Surgery Refusal in Patients with Colorectal Liver Metastases. [PDF]
Andreasen LW +4 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Clinical Characteristics, Antimicrobial Resistance Profiles and Carbapenemases Genotypes of <i>Providencia rettgeri</i>: A 5-Year Retrospective Study in a Tertiary Teaching Hospital in Northern China. [PDF]
Li Y +8 more
europepmc +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Prevalence of Work-Related Pain or Discomfort Among Urologists in the State of Florida: Results From the Florida Urologic Society Task Force on Ergonomic Challenges Experienced by Its Members. [PDF]
David J +11 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Emotion regulation in prolonged grief disorder in later life: Protocol and rationale for a longitudinal neuroimaging study. [PDF]
Hwang G +10 more
europepmc +1 more source

