Results 71 to 80 of about 24,043,177 (284)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Impact of gillnet soaking time on survival, stress physiology, and muscle quality in Atlantic Cod (Gadus morhua)

open access: yesAnimal Welfare
The aim of this study was to investigate the effects of gillnet soak time to gain a better understanding of fish welfare, mortality, stress, and quality (as measured as muscle haemoglobin) during experimental gillnet fishery of Atlantic cod (Gadus morhua)
Ragnhild Aven Svalheim   +2 more
doaj   +1 more source

One-tissue compartment model for myocardial perfusion quantification with N-13 ammonia PET provides matching results: A cross-comparison between Carimas, FlowQuant, and PMOD. [PDF]

open access: yesJ Nucl Cardiol, 2022
Nesterov SV   +10 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Disposición SPyGE N° 13/2018. Autoriza convocatoria.

open access: yes, 2018
Fil: Secretaría de Programación y Gestión Estratégica (P). Universidad Nacional de Río Negro. Río Negro, ArgentinaDisposición SPyGE N° 13/2018. Autoriza la convocatoria para la realización de una contratación para la adquisición de equipamiento para el ...
Secretaría de Programación y Gestión Estratégica (P)
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Resolução n. 15, de 30 de setembro de 2014 [PDF]

open access: yes, 2014
Altera a redação dada pela Resolução n. 9/ENAMAT, de 15 de dezembro de 2011, e pela Resolução n. 13/ENAMAT, de 13 de dezembro de 2013, que tratam da Formação Continuada dos Magistrados do Trabalho.Determina a republicação da Resolução n.
Escola Nacional de Formação e Aperfeiçoamento de Magistrados do Trabalho (Brasil) (Enamat)
core  

Cu n Clusters (n = 13, 43, and 55) as Possible Degradant Agents of mSF6 Molecules (m = 1, 2): A DFT Study. [PDF]

open access: yesACS Omega, 2022
Sintillo SM   +4 more
europepmc   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Le Conseil constitutionnel valide la loi n° 2011-835 du 13 juillet 2011

open access: yes, 2013
International audienceLoi portant interdiction de la fracturation hydraulique pour l'exploration et l'exploitation des ...
Laffaille, Franck
core  

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