In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Expediente V.10 N°20 jul/dez 2016
História em Reflexão
doaj
Effects of a Group-Based Cognitive Behavioral Therapy for Sleep in Nursing Students: Pilot Randomized Controlled Trial. [PDF]
Pérez-Manchón D +3 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
From risk classification to clinical action: a prespecified paired pilot benchmark of public large language model interfaces for diabetes-related foot ulcer prevention. [PDF]
Wen Y +7 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Pain Management in Older Adults: An Interprofessional Training Approach Assessed by Script Concordance Tests. [PDF]
Meurant A +4 more
europepmc +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Prehospital Emergency Care for Traumatic Brain Injury Patients in Hanoi: A Multicenter Study of Outcomes and Quality of Care. [PDF]
Hoang BH +4 more
europepmc +1 more source

