Results 221 to 230 of about 26,531,108 (240)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Effectiveness of Lactobacillus-supplemented eradication therapy for Helicobacter pylori: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Eur J Clin Pharmacol
Moore KMH, Santo P, Holanda EU, Nau AL, Meine GC.   +4 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

['Lógoi Magazine 19/20', 'Revista Lógoi N° 19/20']

Lógoi, 2015
Revista Lógoi
doaj  

Fluorescence-guided lymphadenectomy in gastric cancer surgery: a novel intraoperative indocyanine green injection. [PDF]

Arq Bras Cir Dig
Lanzarini E, Cruz E, Sallaberry P, Gaete D, Fernández I, Musleh M.   +5 more
europepmc   +1 more source

Nitrogen uptake from soil residual fertilizer by subsequent crops: regulatory effects of previous nitrogen application rate and subsequent irrigation regime. [PDF]

Front Plant Sci
Xu X, Chen J, Cai Y, Tian Y, Zhang E, Hou M, Zhong F, Lu J, Li J.   +8 more
europepmc   +1 more source

Predictors of response to mepolizumab for severe asthma: a REDES study post hoc analysis. [PDF]

BMJ Open
Blanco-Aparicio M, Carrillo-Diaz T, Martinez-Moragon E, Bañas-Conejero D, Sánchez-Herrero MG, Domingo-Ribas C, REDES study group.   +6 more
europepmc   +1 more source

Editorial V.20 N.51

Revista de Ciências da Administração : RCA, 2018
Gabriela Fiates
doaj  

Salvage Metastasis-Directed Therapy Without Androgen Deprivation for Positron Emission Tomography-Defined Oligorecurrent Prostate Cancer: Results of the SOAR Phase II Trial. [PDF]

JU Open Plus
Crockett E, Schmidt B, Rodriguez O, Taylor A, Braun E, Leonhart S, Swami U, Boucher KM, Chapman L, Davis H, Linton J, Mangelson E, Johnson S, Tward J, Odei B, Yap J, Gupta S, Kohli M, Agarwal N, Dechet C, O'Neil B, Maughan BL, Sanchez A.   +22 more
europepmc   +1 more source

Editorial V.20 N.50

Revista de Ciências da Administração : RCA, 2018
Gabriela Fiates
doaj