Results 161 to 170 of about 19,433,217 (243)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Statesman, V. 33, n. 30

, 1990
v. : ill.; 32 cm (original analog pub.)Archived web contentThe digital publication of the Stony Brook Statesman was made possible through the kind support of The Stony Brook Alumni ...
Stony Brook University Statesman
core  

Pediatric autoimmune hemolytic anemia is associated with a high incidence of underlying immune disorders. [PDF]

Blood Adv
Harris EM, Steele M, Kalashnikova T, Badawy SM, Pavalagantharajah S, Hillier K, Klaassen RJ, Kalter JA, Rothman JA, McComb C, Shah SJ, Shimano KA, Bloom EJ, Khan A, Elkus H, Breakey VR, Fritch Lilla SA, Leister J, Kochhar M, Young O, Phillips L, Chumsky J, Ghanem D, Charland D, Nakano TA, Remiker A, Everly CJ, Matsunaga A, Tiu GC, Valle RP, Nataraj S, Rifkin-Zenenberg S, Tavares E, Montcrieff C, Chen N, London WB, Lambert MP, Grace RF.   +37 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Statesman, V. 33, n. 03

, 1989
v. : ill.; 32 cm (original analog pub.)Archived web contentThe digital publication of the Stony Brook Statesman was made possible through the kind support of The Stony Brook Alumni ...
Stony Brook University Statesman
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

An Estrogen-IL-33 Circuit in Aortic Fibroblasts Underlies Sex Differences in Tregs in Abdominal Aortic Aneurysm. [PDF]

JACC Basic Transl Sci
Hu W, Li J, Zhai L, Chen Z, Ye L, Xia N, Tang T, Nie S, Zhang M, Jiao J, Lv B, Yang F, Lu Y, Zha L, Gu M, Hu X, Wen S, Li D, Hu D, Wang W, Chen C, Wang QK, Shan Z, Ji Y, Cheng X.   +24 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Derrame pleural por Trichomonas en paciente con bronquiectasias

Open Respiratory Archives, 2020
Alma Iris Cano Rodríguez, Hazael Jimenez Amador   +1 more
doaj   +1 more source

Early Growth Response 1-Associated Epithelial Autophagy-Related Changes in Allergic Airway Inflammation. [PDF]

Pediatr Discov
Wang X, Ren J, Zhao Y, Luo Z.
europepmc   +1 more source