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Disposición SPyGE N° 53/2022. Aprobar la Documentación Técnica y el Presupuesto Oficial
Fil: Secretaría de Programación y Gestión Estratégica (P). Universidad Nacional de Río Negro. Río Negro, ArgentinaDisposición SPyGE N° 53/2022. Aprobar la Documentación Técnica y el Presupuesto Oficial, realizado por la Subsecretaría de Infraestructura ...
Secretaría de Programación y Gestión Estratégica (P)
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Fil: Consejo Superior de Programación y Gestión Estratégica (P). Universidad Nacional de Río Negro. Río Negro, ArgentinaResolución CSPyGE N° 53/2021.
Consejo Superior de Programación y Gestión Estratégica (P)
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Resolución CSPyGE N° 53/2020. Desestima Recurso Jerárquico.
Fil: Consejo Superior de Programación y Gestión Estratégica (P). Universidad Nacional de Río Negro. Río Negro, ArgentinaResolución CSPyGE N° 53/2020.
Consejo Superior de Programación y Gestión Estratégica (P)
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ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

