Results 51 to 60 of about 738,909 (270)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Combined Reinforcement Learning via Abstract Representations
, 2018 In the quest for efficient and robust reinforcement learning methods, both model-free and model-based approaches offer advantages. In this paper we propose a new way of explicitly bridging both approaches via a shared low-dimensional learned encoding of ...
Bengio, Yoshua +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
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, 2018 Department of Energy Engineering (Battery Science and Technology)The continuous throng in demand for high energy density rechargeable batteries innovatively drives technological development in cell design as well as electrochemically active materials. In
Jeong, Dae-Hyeon
core
, 2016 This paper considers hybrid beamforming (HB) for downlink multiuser massive multiple input multiple output (MIMO) systems with frequency selective channels.
Bogale, Tadilo Endeshaw +3 more
core +1 more source
2025 IEEE/CVF Winter Conference on Applications of Computer Vision (WACV)Neural Architecture Search (NAS) continues to serve a key roll in the design and development of neural networks for task specific deployment. Modern NAS techniques struggle to deal with ever increasing search space complexity and compute cost constraints.
Sridhar, Arjun, Chen, Yiran
openaire +2 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
E3S Web of Conferences, 2018 Khreschatyk is a page apart in the history of world architecture. While it has a number of distinct characteristics of totalitarian architecture, Khreschatyk is the only architectural ensemble of the period to combine na-tional tradition with the exalted
Oliynyk Olena
doaj +1 more source
Energies, 2022 Energy efficiency is extremely significant for industrial processes and technologies. Rising energy prices, depleting fossil fuels, as well as tightening regulations that impose the need to reduce GHG emissions incentivize companies to look for energy ...
Grzegorz Bartnicki +3 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source