Results 61 to 70 of about 738,909 (270)

The G.R.A.D. Programme: an alternative form of practice [PDF]

open access: yes, 2012
The Graduate Retention And Development (G.R.A.D.) Programme was a response to the difficulty which many architecture graduates were having in securing relevant work.
Messer, Sebastian
core  

Tensor Regression Networks [PDF]

open access: yes, 2020
Convolutional neural networks typically consist of many convolutional layers followed by one or more fully connected layers. While convolutional layers map between high-order activation tensors, the fully connected layers operate on flattened activation ...
Anandkumar, Anima   +5 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Arquitectura Colaborativa. Una Aproximación al Tema a Través de 4 Casos

open access: yesRevista Internacional de Educación para la Justicia Social, 2017
En este escrito propongo aportar a la generación de enfoques alternativos sobre la arquitectura como práctica pedagógica en ámbitos extradisciplinares.
Javier Samaniego
doaj   +1 more source

Architektura cerkiewna na Ukrainie 1991–2022

open access: yesKultura Słowian, 2023
Po upadku ZSSR nastąpiła na Ukrainie prawdziwa eksplozja budownictwa sakralnego. Artykuł, o charakterze przeglądowym, prezentuje czternaście spośród blisko tysiąca cerkwi zbudowanych na Ukrainie w ...
Bp Michał Janocha
doaj   +1 more source

Finding Competitive Network Architectures Within a Day Using UCT

open access: yes, 2018
The design of neural network architectures for a new data set is a laborious task which requires human deep learning expertise. In order to make deep learning available for a broader audience, automated methods for finding a neural network architecture ...
Wistuba, Martin
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A Taxonomy of Self-configuring Service Discovery Systems [PDF]

open access: yes, 2007
We analyze the fundamental concepts and issues in service discovery. This analysis places service discovery in the context of distributed systems by describing service discovery as a third generation naming system.
Hartel, P.H.   +2 more
core   +1 more source

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