Results 141 to 150 of about 155,744 (263)
Abstract Proton (1H) magnetic resonance spectroscopy (MRS) is a non‐invasive imaging technique that can be used to assess brain metabolism. Establishing reference levels of fetal brain metabolites in a translatable preclinical model is crucial for identifying subtle deviations from normal cerebral development. Herein, we developed a 1H‐MRS protocol for
Jordan A. Minns +10 more
wiley +1 more source
¹H NMR Chemical Shifts and J-Coupling Constants Dependence on Temperature and pH: Implications for the Quantification of Relevant Metabolites. [PDF]
1H MRS, in combination with quantification methods using model functions based on prior knowledge of chemical shifts and coupling constants, allows the determination of characteristic metabolic processes in healthy and diseased tissue. Using the functional relationships δpHT$$ \delta \left( pH,T\right) $$ and JpHT$$ J\left( pH,T\right) $$ enables this ...
Wermter FC, Bock C, Dreher W.
europepmc +2 more sources
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand +2 more
wiley +1 more source
Pengaruh Kosubstrat Tapioka terhadap Serapan Mineral Jamur Tiram Putih
Sandra Hermanto, Irawan Sugoro
doaj +1 more source
Simultaneous Detection of GABA and Glycine Using MEGA‐PRESS With TE Optimization at 3T
ABSTRACT Purpose To achieve the simultaneous acquisition of gamma‐aminobutyric acid (GABA) and glycine (Gly) using a MEGA‐PRESS sequence with an optimized TE at 3T. Methods MEGA‐PRESS simulations were performed at TEs 60‐88 ms to determine the optimal TE for Gly detection with minimal myo‐Inositol (mI) overlap and maximal GABA detection sensitivity ...
Justin R. Singer, Kimberly L. Chan
wiley +1 more source
Abstract Air separation via selective adsorption using porous adsorbents offers energy‐efficient alternatives to cryogenic distillation for producing high‐purity O2 and N2. Adsorbent efficacy depends on balancing selectivity, durability, and performance consistency across varying conditions. This comprehensive review critically discusses the design and
Tianqi Wang +9 more
wiley +1 more source
Differentiating Creatine and Phosphocreatine In Vivo Using 3 T 1H MR Spectroscopy
ABSTRACT Purpose Validation and improvements to the proton MR spectroscopic measurement of creatine and phosphocreatine in vivo at 3 T. Methods Spectral simulations were used to evaluate and explore the mitigation of LCModel fitting bias due to lineshape, signal‐to‐noise (SNR) and non‐metabolite backgrounds with a focus on phosphocreatine and the ...
Ralph E. Hurd +9 more
wiley +1 more source
Identifying Out‐of‐Voxel Echoes in Edited MRS With Phase Cycle Inversion
ABSTRACT Purpose To identify the origin of out‐of‐voxel (OOV) signals based on the coherence transfer pathway (CTP) formalism using signal phase conferred by the acquisition phase cycling scheme. Knowing the CTP driving OOV artifacts enables optimization of crusher gradients to improve their suppression.
Zahra Shams +14 more
wiley +1 more source
Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study
Combined metabolomic analysis of the intracellular and extracellular portions of SH‐SY5Y cells revealed that, in the presence of Aβ 1–42, nicotine primarily influences pathways related to neurotransmission, energy metabolism, as well as the biosynthesis and degradation of membrane phospholipids.
Enza Napolitano +5 more
wiley +1 more source

