Results 101 to 110 of about 1,203,004 (255)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
, 2018 Constructing electrode materials with three-dimensional (3D) configurations has been presented as a promising way to achieve excellent properties in energy storage.
Xueyong Ding (4992887) +9 more
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Screening of tropical maize for salt stress tolerance
Crop Breeding and Applied Biotechnology, 2007 Since salinity is a common stress factor in agricultural areas, the objective of this study was to evaluate the feasibility of morphological and physiological traits as selection criteria of maize genotypes under salt stress. The experiments were carried
Carlos Daniel Giaveno +3 more
doaj
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Introduction to dossier Foreign and defense policies in Latin America: Towards a new regionalism
, 2020 Univ Nacl Rosario, Rosario, Santa Fe, ArgentinaConsejo Nacl Invest Cient & Tecn CONICET, Buenos Aires, DF, ArgentinaUniv Estadual Paulista UNESP, Sao Paulo, BrazilConsejo Nacl Desarrollo Cient & Tecnol CNPq, Sao Paulo, BrazilUniv Estadual Paulista UNESP,
Alves-Soares, Samuel [UNESP] +1 more
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Perovskite solar cells are one of the most attractive alternative photovoltaic technologies. Moreover, the cells can be manufactured simply and inexpensively using solution-based methods and low-cost precursors. However, solution-based methods frequently
Atcharawon Gardchareon (1904143) +8 more
core +1 more source