Results 121 to 130 of about 1,151,690 (319)

Introduction to dossier Foreign and defense policies in Latin America: Towards a new regionalism

open access: yes, 2020
Univ Nacl Rosario, Rosario, Santa Fe, ArgentinaConsejo Nacl Invest Cient & Tecn CONICET, Buenos Aires, DF, ArgentinaUniv Estadual Paulista UNESP, Sao Paulo, BrazilConsejo Nacl Desarrollo Cient & Tecnol CNPq, Sao Paulo, BrazilUniv Estadual Paulista UNESP,
Alves-Soares, Samuel [UNESP]   +1 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Environmental influences on organotin-yeast interactions [PDF]

open access: yes, 2002
As a consequence of the widespread industrial and agricultural applications of organotin compounds, contamination of various ecosystems has occurred in recent decades.
White, Jane S.
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Effect of salt concentrations on the growth of heat-stressed and unstressed escherichia coli

open access: yes, 2009
The effect sodium chloride (NaCl) and potassium chloride (KCl) concentration on the growth of Escherichia coli cells cultivated at 37 and 44°C was studied in an effort to understand the importance of the salts and glucose in medium to the growth of E ...
Abdulkarim, S.M.   +2 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Pengaruh Pre-Cooling dan Perendaman CaCl2, NaCl, serta Ca(OH)2 terhadap Kualitas Fisik-Kimia Cabai Rawit (Capsicum frutescens) selama Penyimpanan Beku

open access: yesJurnal Pangan dan Agroindustri
Bird’s eye chili (Capsicum frutescens) has high economic value in Indonesia, but fluctuating supply causes price instability and challenges for MSMEs. This study evaluated the effects of pre-cooling and soaking in CaCl₂, NaCl, and Ca(OH)₂ solutions on ...
Dego Yusa Ali, Aizahwa Imanukha
doaj   +1 more source

NaCl: for the safer in vivo use of antibacterial silver based nanoparticles

open access: yes, 2018
Mingzhuo Liu,1 Huiqing Zhang,1 Xiangwei Song,2 Chaochao Wei,2 Zhenfang Xiong,3 Fen Yu,2 Chen Li,4 Fanrong Ai,5 Guanghua Guo,1,* Xiaolei Wang2,* 1Department of Burns, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, China ...
Wei CC   +9 more
core  

Home - About - Disclaimer - Privacy