Results 101 to 110 of about 299,285 (291)

De novo NAD+ synthesis enhances mitochondrial function and improves health

open access: yesNature, 2018
Nicotinamide adenine dinucleotide (NAD+) is a co-substrate for several enzymes, including the sirtuin family of NAD+-dependent protein deacylases. Beneficial effects of increased NAD+ levels and sirtuin activation on mitochondrial homeostasis, organismal
E. Katsyuba   +18 more
semanticscholar   +1 more source

Transformations of spatial relationships in elementary education: A case study of changes in two Czech rural areas since the second half of the 20th century

open access: yesMoravian Geographical Reports, 2015
Transformations in the spatial organization of elementary education in the Czech Republic over the last 50 years are examined in this article, via case studies of two rural regions (Turnov district and Zábřeh district).
Kučerová Silvie R.   +2 more
doaj   +1 more source

Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism

open access: yesFrontiers in Cell and Developmental Biology, 2020
NAD+, a co-enzyme involved in a great deal of biochemical reactions, has been found to be a network node of diverse biological processes. In mammalian cells, NAD+ is synthetized, predominantly through NMN, to replenish the consumption by NADase ...
Weiqi Hong   +4 more
semanticscholar   +1 more source

Rozmyślania nad maską

open access: yesPamiętnik Teatralny, 2021
Artykuł zamiast klasycznej recenzji monografii naukowej proponuje serię rozmyślań nad wybranymi wątkami książki Wojciecha Dudzika Maska w kulturze współczesnej Europy: Teorie i praktyki (Warszawa: Wydawnictwo Naukowe PWN 2020). Subiektywny wybór tematów wprawdzie tylko częściowo oddaje bogactwo problemów poruszanych przez Dudzika, ale wiele ...
openaire   +4 more sources

NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Alzheimer’s disease (AD) is the most common form of dementia, and there is no cure. DNA repair activity is deficient in AD patient brains, especially DNA polymerase β (Polβ), a key protein in DNA base excision.
Yujun Hou   +12 more
semanticscholar   +1 more source

Development and implementation of the concept of disproportionate costs in water management in Central Europe in the light of the EU WFD

open access: yesWater Alternatives, 2020
Many Central European water bodies that failed to achieve the good ecological and chemical status required by the Water Framework Directive in the first management cycle are expected to again fail in the second cycle.
Jan Macháč   +2 more
doaj  

Numerical solvers and cryptanalysis

open access: yesJournal of Mathematical Cryptology, 2009
In this paper, we present an approach to apply numerical methods in the cryptanalysis of modern cryptographic algorithms. We focus on the stream cipher Trivium. It is a stream cipher recommended by the eStream project in the hardware category.
Lamberger Mario   +2 more
doaj   +1 more source

On the sensitivities dependence in non-autonomous dynamical systems [PDF]

open access: yesarXiv, 2016
For discrete autonomous dynamical systems (ADS) $(X, d, f)$, it was found that in the three conditions defining Devaney chaos, topological transitivity and dense periodic points together imply sensitive dependence on initial condition(Banks, Brooks, Cairns, Davis and Stacey, 1992). In this paper, the result of Banks et al.
arxiv  

The Žďár nad Sázavou meteorite fall: Fireball trajectory, photometry, dynamics, fragmentation, orbit, and meteorite recovery [PDF]

open access: yes, 2019
We report a comprehensive analysis of the instrumentally observed meteorite fall \v{Z}\v{d}\'ar nad S\'azavou, which occurred in the Czech Republic on 9 December 2014 at 16:16:45-54 UT. The original meteoroid with an estimated initial mass of 150 kg entered the atmosphere with a speed of 21.89 km/s and began a luminous trajectory at an altitude of 98 ...
arxiv   +1 more source

De novo NAD+ biosynthetic impairment in acute kidney injury in humans

open access: yesNature Network Boston, 2018
Nicotinamide adenine dinucleotide (NAD+) extends longevity in experimental organisms, raising interest in its impact on human health. De novo NAD+ biosynthesis from tryptophan is evolutionarily conserved yet considered supplanted among higher species by ...
Ali Poyan Mehr   +20 more
semanticscholar   +1 more source

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