Transcriptional Heterogeneity of Cryptococcus gattii VGII Compared with Non-VGII Lineages Underpins Key Pathogenicity Pathways [PDF]
We thank Jose Munoz for his input on the analysis of the mouse RNA-seq enrichment. R.A.F. was supported by a Wellcome Trust-Massachusetts Institute of Technology (MIT) Postdoctoral Fellowship. M.C.F. and J.R.
Balloux, Francois +8 more
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The sunflower HD-Zip transcription factor HAHB4 is up-regulated in darkness, reducing the transcription of photosynthesis-related genes [PDF]
HAHB4 belongs to the sunflower subfamily I of HD-Zip proteins and is involved in drought-tolerance response and ethylene-mediated senescence. Cross-talk between these two processes through this transcription factor was recently described.
Ariel, Federico Damian +4 more
core +1 more source
Effective activation of antioxidant system by immune-relevant factors reversely correlates with apoptosis of Eisenia andrei coelomocytes [PDF]
Oxidative stress is harmful to the microbes but also to the host, and may result in bystander damage or death. Because of this, respiratory burst triggered in phagocytes by pathogens is counteracted by production of antioxidative factors. The aim of this
Homa, Joanna +3 more
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Assessment of Seasonal Variability of Cytochemical Responses to Contaminant Exposure in the Blue Mussel Mytilus edulis (Complex) [PDF]
A selected suite of cytochemical parameters in Mytilus edulis are altered in response to field and laboratory exposure to chemical contaminants.
Casillas, E +3 more
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A comparison between the responses of neutral red and acridine orange: Acridine Orange should be preferential and alternative to neutral red as a dye for the monitoring of contaminants by means of biological sensors [PDF]
The acridine orange (AO) and neutral red (NR) dyes, commonly used as probes to measure the internal pH in acidic vesicles, are compared in this article.
Alessandra Iero +27 more
core +2 more sources
Prediction of Anti-Hiv Activity of Flavanoid Constituents Through PASS [PDF]
Prediction of Activity Spectra for Substances (PASS), a new computer program, has been generated to evaluate the biological activity of four major flavanoids from a medicinal herb, Boesenbergia pandurata Holtt. (Zingiberaceae).
Maridass, Muthiah, et al.
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Naringenin as a potent inhibitor molecule for targeting microtubule affinity-regulating kinase 4 (mark4): a molecular docking and in vitro study for therapeutics of Alzheimer's disease [PDF]
Background: The targeted inhibition of Microtubule Affinity-Regulating Kinase 4 (MARK4) using small molecule inhibitors has emerged as a promising therapeutic approach for diverse diseases, including neurological disorders such as Alzheimer’s disease ...
Alam, Mohammad Zubair +6 more
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Emergent synergistic lysosomal toxicity of chemical mixtures in molluscan blood cells (hemocytes) [PDF]
The problem of effective assessment of risk posed by complex mixtures of toxic chemicals in the environment is a major challenge for government regulators and industry.
Clarke, KR +5 more
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Characterization of Triggerable Quinones for the Development of Enzyme-Responsive Liposomes [PDF]
For decades, there has been a lot of focus on the development of new carriers for drug delivery applications. From all of the carriers, stimuli-responsive liposomes have been studied extensively, but only a handful have been enzyme-responsive liposomes ...
Mendoza, Maria Fabiana
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Biomonitoring of Trace Metals in the Coastal Waters Using Bivalve Molluscs [PDF]
Several environmental contaminants including toxic trace metals are being discharged into the coastal environment causing serious threat to marine organisms and posing public health risk.
Krishnakumar, Periyadan K. +2 more
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