Results 41 to 50 of about 142,240 (109)

Identification of Cytochrome P450-Reductase as the Enzyme Responsible for NADPH-Dependent Lucigenin and Tetrazolium Salt Reduction in Rat Epididymal Sperm Preparations1

, 2004
Lucigenin-dependent chemiluminescence and WST-1 reduction can be detected following addition of NADPH to many cell types, including rat epididymal sperm suspensions.
Krutskikh, Anton, Anton Krutskikh, Aitken, R. John, McLaughlin, Eileen A.; id_orcid, Eileen A. McLaughlin, Benjamin J. Curry, R. John Aitken, Curry, Benjamin J., Baker, Mark A., Mark A. Baker   +9 more
core   +1 more source

Tryptophan extends the life of cytochrome P450. [PDF]

Proc Natl Acad Sci U S A, 2023
Ravanfar R, Sheng Y, Gray HB, Winkler JR.   +3 more
europepmc   +1 more source

Cytochrome P450 oxidoreductase participates in nitric oxide consumption by rat brain [PDF]

, 2009
In low nanomolar concentrations, NO (nitric oxide) functions as a transmitter in brain and other tissues, whereas near-micromolar NO concentrations are associated with toxicity and cell death.
Keynes, R.G., Catherine N. Hall, Robert G. Keynes, Hall, C.N., Garthwaite, J., John Garthwaite   +5 more
core  

Engineering of pyridine nucleotide specificity of nitrate reductase: Mutagenesis of recombinant cytochrome b reductase fragment of Neurospora crassa NADPH:Nitrate reductase

, 1998
The cytochrome b reductase fragment of Neurospora crassa NADPH:nitrate reductase (EC 1.6.6.3) was overexpressed in Escherichia coli with a His-tag for purification after mutation of the NADPH binding site.
Shiraishi, Naomasa, Croy, Cynthia, Campbell, Wilbur H., Kaur, John   +3 more
core   +1 more source

Vanadate as a futile, superoxide ion-producing substrate of trypanothione reductase from Trypanosoma cruzi

, 2005
Recombinant Trypanosoma cruzi trypanothione reductase can oxidize NADPH in a futile cycle in the presence of vanadate ion as a result of the generation of reactive oxygen and other radical species from the active site dithiol and the NADPH.
Seddon, Gavin Malcolm, Khan, Mohammed Omar Faruk, Douglas, Kenneth Thomas; id_orcid, Parveen, Seheli   +3 more
core   +1 more source

Does Inhibition of Aldose Reductase Contribute to the Anti-Inflammatory Action of Setipiprant?

, 2017
The aim of this study was to investigate aldose reductase inhibitory action of setipiprant as a potential additional mechanism contributing to its anti-inflammatory action. Aldose reductase activity was determined by spectrophotometric measuring of NADPH
Majekova, M., Ballekova, J., Stefek, M., Soltesova-Prnova, M.   +3 more
core   +1 more source

Relationships between NADPH diaphorase staining and neuronal, endothelial, and inducible nitric oxide synthase and cytochrome P450 reductase immunoreactivities in guinea-pig tissues

, 1997
Relationships between NADPH diaphorase staining and neuronal, endothelial, and inducible nitric oxide synthase and cytochrome P450 reductase immunoreactivities in guinea-pig ...
Ramani Narayanasami (19465594), W Ross Tracey (19465600), Anna J O'Brien (19465582), Daniela Ciampoli (19465585), HM Young (15956489), John Furness (13070439), Timothy J McCabe (19465591), Bettie Sue S Masters (19465597), James P Hardwick (19465588)   +8 more
core  

The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus. [PDF]

Antimicrob Agents Chemother, 2023
Kühbacher A, Merschak P, Haas H, Liebl M, Müller C, Gsaller F.   +5 more
europepmc   +1 more source

On 'Evidence for the participation of cytochrome b5 in hepatic microsomal mixed-function oxidation reactions' by Alfred Hildebrandt and Ronald W. Estabrook. [PDF]

Arch Biochem Biophys, 2022
Guengerich FP.
europepmc   +1 more source

Tryptophan-96 in cytochrome P450 BM3 plays a key role in enzyme survival. [PDF]

FEBS Lett, 2023
Ravanfar R, Sheng Y, Gray HB, Winkler JR.   +3 more
europepmc   +1 more source