Results 191 to 200 of about 425,673 (381)

Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes.

, 1985
Daniel L. Simmons, P.A. Lalley, Charles B. Kasper   +2 more
openalex   +1 more source

dVGLUT Is a Mediator of Sex Differences in Dopamine Neuron Mitochondrial Function Across Aging and in a Parkinson's Disease Model

Aging Cell, EarlyView.
We examined sex and regional differences in mitochondrial reactive oxygen species (ROS) generation and their implications for dopamine (DA) neuron resilience using the Drosophila model. We found: (1) higher basal ROS in males versus females; (2) age‐related ROS increases in both sexes; and (3) DA neuron‐specific dVGLUT RNAi knockdown raised ROS in ...
Silas A. Buck, Samuel J. Mabry, Tenzin Kunkhyen, Zilu Yang, Sophie A. Rubin, Jinting Yang, Claire E. J. Cheetham, Zachary Freyberg   +7 more
wiley   +1 more source

Molecular components of PAMP-triggered oxidative burst in plant immunity [PDF]

, 2009
Reactive oxygen species (ROS) are important molecules that are rapidly generated in response to abiotic and biotic stimuli and which regulate diverse physiological processes such as stomatal aperture and cell death.
Mersmann, Sophia
core  

Therapeutic potential of hesperidin in diabetes mellitus‐induced erectile dysfunction through Nrf2‐mediated ferroptosis and oxidative stress

Andrology, EarlyView.
Abstract Background Among erectile dysfunction (ED) caused by metabolic abnormalities, diabetes mellitus‐induced ED (DMED) progresses rapidly, manifests with severe symptoms, and shows reduced responsiveness to conventional medications. Hyperglycemia in the corpus cavernosum has been linked to the induction of both ferroptosis and oxidative stress ...
Sheng Xin, Wen Song, Jiaquan Mao, Peng Hu, Zhong Chen, Jihong Liu, Xiaodong Song, Qian Fang, Kai Cui   +8 more
wiley   +1 more source

Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA

Proceedings of the National Academy of Sciences of the United States of America, 2017
Stefan Köster, S. Upadhyay, P. Chandra, K. Papavinasasundaram, Guozhe Yang, Amir Hassan, Steven J. Grigsby, Ekansh Mittal, Heidi S. Park, Victoria C Jones, F. Hsu, M. Jackson, C. Sassetti, J. Philips   +13 more
semanticscholar   +1 more source

Vascular Nox4: a multifarious NADPH oxidase [PDF]

, 2012
Montezano, A.C., Touyz, R.M.
core   +1 more source

Relaxin‐2 improves type I diabetes mellitus‐induced erectile dysfunction in rats by protecting cavernous endothelial and smooth muscle function, and inhibiting penile fibrosis and apoptosis

Andrology, EarlyView.
Abstract Background Diabetes mellitus‐induced erectile dysfunction (DMED) responds poorly to first‐line treatments, necessitating the development of new therapeutic strategies. Relaxin‐2 (RLX‐2) plays a crucial role in protecting vascular endothelium, vasodilatation, and antifibrosis in various diseases.
Bocheng Tu, Kang Liu, Bo Wen, Peng Hu, Taotao Sun, Beining Li, Manan Sulaiman, Shujun Jiang, Tao Wang, Jihong Liu, Yang Luan   +10 more
wiley   +1 more source

Involvement of GTP in cell-free activation of neutrophil NADPH oxidase. Studies with GTP analogues [PDF]

, 1992
E Klinger, Irit Aviram
openalex   +1 more source

Therapeutic potential of NADPH oxidase 1/4 inhibitors

British Journal of Pharmacology, 2017
G. Teixeira, C. Szyndralewiez, S. Molango, S. Carnésecchi, F. Heitz, P. Wiesel, J. M. Wood   +6 more
semanticscholar   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source