Results 191 to 200 of about 442,921 (391)

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

open access: yesMed Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang   +22 more
wiley   +1 more source

Identification and Characterization of a Novel NADPH Oxidase 1 (Nox1) Inhibitor That Suppresses Proliferation of Colon and Stomach Cancer Cells

open access: diamond, 2017
Tsuyoshi Yamamoto   +7 more
openalex   +2 more sources

Calcium signaling in plant defense

open access: yesNew Plant Protection, EarlyView.
Calcium signaling acts as a central hub in plant immunity, translating pathogen perception into defense responses. This review highlights the channels, sensors, and signaling networks involved, and discusses how pathogens subvert calcium dynamics, as well as how this knowledge may inspire innovative strategies for engineering durable crop resistance ...
Lifan Sun, Yu Wang, Jie Zhang
wiley   +1 more source

Plasmodesmata‐located proteins: The molecular hubs in noncell‐autonomous immunity

open access: yesNew Plant Protection, EarlyView.
Plasmodesmata serve as critical battlefields for plant immunity, regulated by diverse proteins. This article provides a comprehensive review of the regulatory mechanisms, challenges, and future directions concerning proteins located within plasmodesmata and their roles in plant defense responses.
Zheng Wu, Xiaoyi Shan
wiley   +1 more source

Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

open access: yesAntioxidants and Redox Signaling, 2015
Sebastian Altenhöfer   +4 more
semanticscholar   +1 more source

NADPH oxidase of neutrophils

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1996
Henderson, Lydia M., Chappell, J.Brian
openaire   +2 more sources

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

open access: yesPhytotherapy Research, EarlyView.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao   +13 more
wiley   +1 more source

An NADPH-Oxidase/Polyamine Oxidase Feedback Loop Controls Oxidative Burst Under Salinity1

open access: yesPlant Physiology, 2016
K. Gémes   +7 more
semanticscholar   +1 more source

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