Results 211 to 220 of about 424,484 (404)
Rac Activation Induces NADPH Oxidase Activity in Transgenic COSphox Cells and Level of Superoxide Production is Exchange Factor-Dependent [PDF]
, 2002 Transient expression of constitutively active Rac1 derivatives, (G12V) or (Q61L), was sufficient to induce phagocyte NADPH oxidase activity in a COS-7 cell model in which human cDNAs for essential oxidase components, gp91phox, p22phox, p47phox, and ...
Atkinson, Simon J +3 more
core
FASEB BioAdvances, EarlyView.Prolonged fasting and fibrate treatment induce peroxisomal β‐oxidation and lead to excessive generation of hydrogen peroxide, which stimulates ethanol metabolism and significantly increases the formation of acetaldehyde; further oxidation of acetaldehyde into acetate remarkably elevates the mitochondrial ratio of NADH/NAD+ and causes feedback ...
Yida Zhang +6 more
wiley +1 more source
Nutrient‐induced changes in root respiration in 10 woody plant species
Functional Ecology, Volume 39, Issue 4, Page 1128-1139, April 2025.Read the free Plain Language Summary for this article on the Journal blog. Abstract Nitrogen (N) and phosphorus (P) are soil macronutrients that influence ecosystem productivity through strong impacts on plant metabolism. The influence of nutrient supply on the relationships between leaf respiration rate (R) and leaf N concentration ([N]) has been ...
Deping Zhai +9 more
wiley +1 more source
The A640G CYBA polymorphism associates with subclinical atherosclerosis in diabetes [PDF]
, 2011 Oxidative stress is implicated in diabetes. The NADPH oxidases are the main source of superoxide in phagocytic and vascular cells, and p22phox is a key subunit. Genetic variants of CYBA, the human p22phox gene, associate with cardiovascular disease.
Beloqui, O. (Óscar) +6 more
core
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Activated neutrophils play a crucial role in the development of neutrophilic dermatoses, including pustular psoriasis. Adsorptive granulocyte and monocyte apheresis (GMA) is an effective treatment for skin disorders. Although previous basic research has demonstrated neutrophil activation, no efficient method exists to assess it in
Yuko Higashi +8 more
wiley +1 more source
Vascular Nox4: a multifarious NADPH oxidase [PDF]
, 2012 Montezano, A.C., Touyz, R.M.
core +1 more source
Aging Cell, EarlyView.The role of mitochondrial translocator protein (TSPO) in hippocampal inflammation is age‐dependent, with TSPO deletion drastically exacerbating inflammation in aged mice, while dampening it in young mice. This TSPO–aging interaction was linked to NF‐kβ and interferon regulatory transcriptional networks. TSPO deletion exacerbated age‐dependent depletion
Kei Onn Lai +7 more
wiley +1 more source
Aging Cell, EarlyView.We examined sex and regional differences in mitochondrial reactive oxygen species (ROS) generation and their implications for dopamine (DA) neuron resilience using the Drosophila model. We found: (1) higher basal ROS in males versus females; (2) age‐related ROS increases in both sexes; and (3) DA neuron‐specific dVGLUT RNAi knockdown raised ROS in ...
Silas A. Buck +7 more
wiley +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2017 Stefan Köster +13 more
semanticscholar +1 more source