Results 231 to 240 of about 442,921 (391)

Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis.

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2015
Diptadip Dattaroy, Sahar Pourhoseini, Suvarthi Das, Firas A. Alhasson, R. Seth, M. Nagarkatti, G. Michelotti, A. Diehl, S. Chatterjee   +8 more
semanticscholar   +1 more source

NADPH oxidase (NOX) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, EarlyView.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Organophosphate Chemical Nerve Agents, Oxidative Stress, and NADPH Oxidase Inhibitors: An Overview. [PDF]

Int J Mol Sci
Meyer C, Thippeswamy T.
europepmc   +1 more source

Lycorine protects against inflammatory hemorrhagic skin injury via suppression of neutrophil-driven NADPH oxidase activation

Y. Song, Yaoshuai Zhang, Huixing Li, Wen Li, Yuwen Zhong, Feng Qian, Junyao Yang, Lisong Shen   +7 more
openalex   +1 more source

Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway [PDF]

, 2007
Vicki Thallas‐Bonke, Suzanne R. Thorpe, Melinda T. Coughlan, Kei Fukami, Felicia Y. T. Yap, Karly C. Sourris, Sally A. Penfold, Leon A. Bach, Mark E. Cooper, Josephine M. Forbes   +9 more
openalex   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

The Role of NADPH Oxidase 2 in Leukocytes. [PDF]

Antioxidants (Basel)
Leiding JW, Mathews CE, Arnold DE, Chen J.   +3 more
europepmc   +1 more source

Drug Repurposing Screen Identifies Pimozide as a ROS‐Inducing Therapy With Anti‐Tumor Efficacy in HNSCC PDX Models

Cancer Science, EarlyView.
A drug repurposing screen for reactive oxygen species (ROS)‐inducing compounds identified Pimozide as a potent anti‐tumor agent in head and neck squamous cell carcinoma (HNSCC) patient‐derived xenograft (PDX) models. Combined treatment with paclitaxel markedly reduced undifferentiated tumor cells.
Shogo Okazaki, Shintaro Nakamura, Tomoya Soma, Momoko Yoshikawa, Seiji Asoda, Yurika Nakajima, Kenji Tsuchihashi, Mitsuyo Ohmura, Ryo Goitsuka, Kenichi Imai, Hideyuki Saya, Osamu Nagano, Hiroyuki Ozawa   +12 more
wiley   +1 more source

Correction: 2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α_Mβ2/NADPH oxidase axis-mediated microglial activation. [PDF]

Cell Death Dis
Zhang C, Hou L, Yang J, Che Y, Sun F, Li H, Wang Q.   +6 more
europepmc   +1 more source