Results 241 to 250 of about 48,906 (319)

Activity-regulated growth of motoneurons at the neuromuscular junction is mediated by NADPH oxidases

, 2022
Sobrido-Cameán D, Oswald MCW, Bailey DMD, Mukherjee A, Landgraf M.   +4 more
europepmc   +1 more source

Pathophysiology and Therapeutic Potential of NADPH Oxidases in Ischemic Stroke-Induced Oxidative Stress. [PDF]

Oxid Med Cell Longev, 2021
Duan J, Gao S, Tu S, Lenahan C, Shao A, Sheng J.   +5 more
europepmc   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

Small Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou, Jingyu Yan, Chenying Cui, Yurong Xu, Kaifang Zhang, Meijun Du, Zhuowei Zhang, Xiuping Wu, Bing Li   +8 more
wiley   +1 more source

Neutrophils and NADPH Oxidases Are Major Contributors to Mild but Not Severe Ischemic Acute Kidney Injury in Mice. [PDF]

Int J Mol Sci
Révész C, Kaucsár T, Godó M, Bocskai K, Krenács T, Mócsai A, Szénási G, Hamar P.   +7 more
europepmc   +1 more source

Lymphocyte Migration Through Monolayers of Endothelial Cell Lines Involves VCAM-1 Signaling Via Endothelial Cell NADPH Oxidase [PDF]

, 2000
Heather Matheny, Tracy L. Deem, Joan M. Cook‐Mills   +2 more
openalex   +1 more source

Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies

VIEW, EarlyView.
Traditional disease treatments often face issues such as poor drug targeting and significant side effects, with many complex diseases lacking effective therapies. Our research utilizes tiny nanomaterials to treat diseases by regulating natural cell death processes, improving the immune environment, etc., enabling drugs to act more precisely.
Yiwen Wan, Wangzheqi Zhang, Yan Liao, Chenglong Zhu, Xiaojing Guo, Zui Zou, Mi Li   +6 more
wiley   +1 more source

Protein kinase C-β contributes to NADPH oxidase activation in neutrophils [PDF]

, 2000
Lodewijk V. Dekker, Michael Leitges, Gabriel ALTSCHULER, Nishil MISTRY, Aileen MCDERMOTT, Jürgen Roes, Anthony W. Segal   +6 more
openalex   +1 more source

dVGLUT Is a Mediator of Sex Differences in Dopamine Neuron Mitochondrial Function Across Aging and in a Parkinson's Disease Model

Aging Cell, EarlyView.
We examined sex and regional differences in mitochondrial reactive oxygen species (ROS) generation and their implications for dopamine (DA) neuron resilience using the Drosophila model. We found: (1) higher basal ROS in males versus females; (2) age‐related ROS increases in both sexes; and (3) DA neuron‐specific dVGLUT RNAi knockdown raised ROS in ...
Silas A. Buck, Samuel J. Mabry, Tenzin Kunkhyen, Zilu Yang, Sophie A. Rubin, Jinting Yang, Claire E. J. Cheetham, Zachary Freyberg   +7 more
wiley   +1 more source

Deactivation of neutrophil NADPH oxidase by actin-depolymerizing agents in a cell-free system [PDF]

, 2000
Minoru Tamura, Masamichi Kanno, Yaeta Endo   +2 more
openalex   +1 more source

Identification of Functional Cellular Markers Related to Human Health, Frailty and Chronological Age

Aging Cell, EarlyView.
Human skin fibroblasts in vitro preserve the memory of age and health. ABSTRACT Aging leads to a decline in physiological reserves, an increase in age‐related diseases, reduced functional ability and a shortened healthspan. While molecular markers of chronological aging exist, their link to general health and intrinsic capacity (IC), a composite ...
Chloé Brodeau, Camille Joly, Anaïs Chekroun, Jean Nakhle, Vincent Blase, Nicolas Espagnolle, Cédric Dray, Armelle Yart, Valérie Planat, Margot Tertrais, Julien Fassy, Sophie Guyonnet, Wan‐Hsuan Lu, Philipe de Souto Barreto, Olivier Teste, Marie Tremblay‐Franco, Kamaryn T. Tanner, Alan A. Cohen, Audrey Carriere, Louis Casteilla, Isabelle Ader, IHU HealthAge/Open Science group   +21 more
wiley   +1 more source