The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
Enzymology of Ca2+-Mobilizing Second Messengers Derived from NAD: From NAD Glycohydrolases to (Dual) NADPH Oxidases. [PDF]
Guse AH.
europepmc +1 more source
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho+10 more
wiley +1 more source
Effects of aerobic exercise on cardiac function and gene expression of NADPH oxidases in diaphragm muscle of rats with aortic stenosis-induced heart failure. [PDF]
Janini Gomes M+13 more
europepmc +1 more source
Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3‐kinases: Binding partners of SH3 domains? [PDF]
Chris P. Ponting
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Understanding the Mechanism of Cardiotoxicity Induced by Nanomaterials: A Comprehensive Review
This review provides a bibliometric analysis for understanding the study of nanotoxicity on cardiovascular health. It begins by outlining the pathways through which nanomaterials enter the cardiovascular system, followed by a summary of the mechanisms underlying nanomaterial‐induced cardiotoxicity.
Zaiyong Zheng+7 more
wiley +1 more source
Nox, Nox, Are You There? The Role of NADPH Oxidases in the Peripheral Nervous System. [PDF]
Eid SA+3 more
europepmc +1 more source
Interactions between cytosolic components of the NADPH oxidase: p40phox interacts with both p67phox and p47phox [PDF]
Frans B. Wientjes+3 more
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The regulatory effects of low‐intensity pulsed ultrasound (LIPUS) stimulation in senescent cells are presented. LIPUS perturbs the membrane in senescent cells and induces intracellular reactive oxygen species via NOX4 expression. Consequently, secretion of senescence‐associated secretory phenotype, followed by migration of monocytes/macrophages and ...
HyeRan Gwak+7 more
wiley +1 more source
NADPH Oxidases Are Required for Appressorium-Mediated Penetration in Colletotrichum scovillei-Pepper Fruit Pathosystem. [PDF]
Fu T, Lee NH, Shin JH, Kim KS.
europepmc +1 more source