Results 241 to 250 of about 297,991 (354)

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

open access: yesNature reviews. Drug discovery, 2011
G. Drummond   +3 more
semanticscholar   +1 more source

Genomic context analysis enables the discovery of an unusual NAD‐dependent racemase in phosphonate catabolism

open access: yesThe FEBS Journal, EarlyView.
The authors identify PbfF (previously annotated as a NAD‐dependent dehydrogenase) as a hitherto unknown enzyme in phosphonate catabolism. Guided by genome context analysis, they show that PbfF is actually a racemase, serving to degrade the natural compound (S)‐2‐amino‐1‐hydroxyethylphosphonate (S‐HAEP).
Francesca Ruffolo   +8 more
wiley   +1 more source

Studies of the membrane‐bound flavocytochrome MsrQ flavin mononucleotide (FMN)‐binding site reveal an unexpected ubiquinone cofactor

open access: yesThe FEBS Journal, EarlyView.
The membrane‐bound heme flavoprotein MsrQ is the specific electron donor for the periplasmic methionine sulfoxide reductase MsrP. Analysis of its flavin environment revealed that ubiquinone (UQ) is a cofactor for MsrQ. However, redox studies demonstrate that UQ cannot function as an electron donor for the MsrPQ system.
Philippe Carpentier   +9 more
wiley   +1 more source

Crosstalk Between SMPDL3b and NADPH Oxidases Mediates Radiation-Induced Damage of Renal Podocytes. [PDF]

open access: yesFront Med (Lausanne), 2021
Azzam P   +8 more
europepmc   +1 more source

Calyculin A modulates activation of the NADPH-oxidase in Me2SO-differentiated HL-60 cells [PDF]

open access: gold, 1998
Joo‐In Park   +4 more
openalex   +1 more source

Imeglimin improves hyperglycemia and hypoglycemia‐induced cell death and mitochondrial dysfunction in immortalized adult mouse Schwann IMS32 cells

open access: yesJournal of Diabetes Investigation, EarlyView.
Imeglimin reduces Schwann cell death by suppressing Complex I and oxidative stress, which may prevent diabetic neuropathy by protecting mitochondrial functions. ABSTRACT Aims/Introduction Imeglimin, a novel oral antidiabetic drug, enhances glucose‐stimulated insulin secretion, improves insulin sensitivity, and reduces mitochondrial reactive oxygen ...
Ayako Kato   +10 more
wiley   +1 more source

The TGF-β/NADPH Oxidases Axis in the Regulation of Liver Cell Biology in Health and Disease. [PDF]

open access: yesCells, 2021
Herranz-Itúrbide M   +4 more
europepmc   +1 more source

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