Results 281 to 290 of about 48,906 (319)

Phorbor Myristate Acetate Induces NADPH Oxidase Activity of Cytochalasin B-Primed Neutrophils through the Protein Kinase C-Independent Pathway.

, 2000
Naoko Kawakami, Kenji KITA, Takao Hayakawa, Teruhide Yamaguchi, Sadaki FUJIMOTO   +4 more
openalex   +2 more sources

A Role for High Mobility Group Box 1 (HMGB1) Release in the Pathogenesis of Gastroesophageal Reflux Disease

Neurogastroenterology &Motility, EarlyView.
Incubation of esophageal epithelial cells with a weakly acidic (pH 5) bile salt (deoxycholic acid) induces translocation of HMGB1 from the nucleus to the cytosol, and its subsequent release from the cell. This process can be ameliorated by pre‐treatment with the antioxidant, curcumin.
Tom Leech, David Kelsell, Diana Blaydon, Philip Woodland, Madusha Peiris   +4 more
wiley   +1 more source

Abnormal Homeostasis in the Redox State and Related Signaling Pathways, in Irritable Bowel Syndrome

Neurogastroenterology &Motility, EarlyView.
There is higher oxidative stress and higher expression of transcription factor NF‐κB and the gp91 subunit of NADPH oxidase in IBS, with lower antioxidant regulator Nrf2. There are no differences in the IBS subtypes; however, in IBS‐C, malondialdehyde correlated with IL‐4, and TNF‐α with IL‐10, suggesting an interleukin‐mediated anti low‐grade ...
A. S. Morales‐Guzmán, A. Alarcón‐Aguilar, A. Luna‐López, A. D. Santana‐Vargas, M. Motola‐Kuba, R. Librado‐Osorio, J. A. García‐Álvarez, M. J. Schmulson   +7 more
wiley   +1 more source

Reactive oxygen species act as signaling molecules to control root hair initiation and tip growth

New Phytologist, EarlyView.
Summary Root hairs (RHs) increase the surface area of roots, facilitating nutrient and water uptake and plant anchorage. RHs form from root epidermal cells and elongate by polar tip growth. Reactive oxygen species (ROS) have recently been implicated as important signals that drive RH formation and elongation using both genetic and imaging approaches ...
Megan E. Gerber, Maleana G. White, Gloria K. Muday   +2 more
wiley   +1 more source

ARABIDOPSIS HOMOLOG OF TRITHORAX1 impacts lateral root development by epigenetic regulation of targets involved in root system architecture

New Phytologist, EarlyView.
Summary Developmental processes are regulated at multiple levels, including the epigenetic level. Among the epigenetic factors, histone H3 lysine 4 (H3K4) methyltransferases contribute to active transcription of target genes, and here, we explored how the H3K4 methyltransferase ARABIDOPSIS HOMOLOG OF TRITHORAX1 (ATX1) affects Arabidopsis thaliana ...
Selene Napsucialy‐Mendivil, Héctor H. Torres‐Martínez, Gustavo Rodríguez‐Alonso, Diana Marcela Rivera‐Toro, Raúl Alvarez‐Venegas, Marco Adán Júarez‐Verdayes, Svetlana Shishkova, Joseph G. Dubrovsky   +7 more
wiley   +1 more source

Redox regulation of LSD1/CATALASE 2 phase separation condensates controls location and functions

New Phytologist, EarlyView.
Summary Phase separation of proteins into membraneless compartments is emerging as an important mechanism of plant developmental and stress responses. We show Arabidopsis catalase 2 (CAT2) is recruited to phase‐separated condensates with LESION SIMULATING DISEASE1 (LSD1), a plant‐specific regulator of programmed cell death, in a redox‐dependent manner ...
Chi‐Chuan Lin, Christine H. Foyer, Megan Wright, Alison Baker   +3 more
wiley   +1 more source

MLO‐mediated Ca2+ influx regulates root hair tip growth in Arabidopsis

New Phytologist, EarlyView.
Summary Root hair tip‐growth involves coordinated Ca2+ and ROS signaling to promote growth while maintaining tip integrity. MILDEW RESISTANCE LOCUS‐O (MLO) proteins act downstream of FERONIA (FER) receptor‐like kinases in pollen tubes and synergids to regulate calcium dynamics.
Sienna T. Ogawa, Weiwei Zhang, Christopher J. Staiger, Sharon A. Kessler   +3 more
wiley   +1 more source

Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus‐like particles

Plant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana. Relying on bacterial vector Agrobacterium tumefaciens, this process is favoured by co‐expression of viral silencing suppressor
Louis‐Philippe Hamel, Francis Poirier‐Gravel, Marie‐Ève Paré, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Dominique Michaud, Marc‐André D'Aoust   +9 more
wiley   +1 more source

The clarification of two hydroxylation steps in the conversion of cholesterol to OSW‐1 in Ornithogalum saundersiae

Plant Biotechnology Journal, EarlyView.
Summary OSW‐1 is a cholestane saponin uniquely produced in Ornithogalum saundersiae and exhibits a potential antitumor activity. The enzymes responsible for OSW‐1 biosynthesis in O. saundersiae, however, remain unclear. Herein, cholesterol was confirmed to be the precursor of OSW‐1 using stable‐isotope labeling method.
Shu‐Yue Zhang, Jian‐Qiang Kong
wiley   +1 more source

Expression of a constitutively active nitrate reductase increases SARS‐CoV‐2 Spike protein production in Nicotiana benthamiana leaves that otherwise show traits of senescence

Plant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the Spike (S) protein of Severe Acute Respiratory Syndrome Coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana, a process promoted by the co‐expression of viral silencing suppressor P19.
Louis‐Philippe Hamel, Marie‐Ève Paré, Francis Poirier‐Gravel, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Marc‐André D'Aoust, Dominique Michaud   +9 more
wiley   +1 more source