Results 301 to 310 of about 51,121 (339)
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Blood, 1999
T HE NADPH OXIDASES are a group of plasma membrane–associated enzymes found in a variety of cells of mesodermal origin. The most thoroughly studied of these is the leukocyte NADPH oxidase, which is found in professional phagocytes and B lymphocytes.
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T HE NADPH OXIDASES are a group of plasma membrane–associated enzymes found in a variety of cells of mesodermal origin. The most thoroughly studied of these is the leukocyte NADPH oxidase, which is found in professional phagocytes and B lymphocytes.
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Antioxidants & Redox Signaling, 2006
NADPH oxidases have a distinct cellular localization in the kidney. Reactive oxygen species (ROS) are produced in the kidney by fibroblasts, endothelial cells (EC), vascular smooth muscle cells (VSMC), mesangial cells (MCs), tubular cells, and podocyte cells.
Pritmohinder S, Gill +1 more
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NADPH oxidases have a distinct cellular localization in the kidney. Reactive oxygen species (ROS) are produced in the kidney by fibroblasts, endothelial cells (EC), vascular smooth muscle cells (VSMC), mesangial cells (MCs), tubular cells, and podocyte cells.
Pritmohinder S, Gill +1 more
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NADPH oxidase and heart failure
Current Opinion in Pharmacology, 2006Reactive oxygen species play important roles in the pathophysiology of chronic heart failure secondary to chronic left ventricular hypertrophy or myocardial infarction. Reactive oxygen species influence several components of the phenotype of the failing heart, including contractile function, interstitial fibrosis, endothelial dysfunction and myocyte ...
Murdoch, Colin E. +4 more
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Role of Nadph Oxidase in Atherosclerosis
Future Cardiology, 2008Reactive oxidant species (ROS) seem to play a key role in the atherosclerotic process via a series of molecular changes that lead to macrophage infiltration in the endothelium and eventually to plaque formation. ROS are also implicated in arterial dysfunction via inactivation of nitric oxide, a potent vasodilator and antiaggregating molecule produced ...
VIOLI, Francesco +3 more
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Localizing NADPH Oxidase–Derived ROS
Science's STKE, 2006Reactive oxygen species (ROS) function as signaling molecules to mediate various biological responses, including cell migration, growth, and gene expression. ROS are diffusible and short-lived molecules. Thus, localizing the ROS signal at the specific subcellular compartment is essential for activating redox signaling events after receptor activation ...
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Journal of clinical pathology, 2002
Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species.
Van Heerebeek, L +5 more
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Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species.
Van Heerebeek, L +5 more
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NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications
Signal Transduction and Targeted Therapy, 2020Huai-Qiang Ju, Dan Xie, Rui-Hua Xu
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Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
Nature Reviews Molecular Cell Biology, 2020Helmut Sies, Dean P Jones
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