Results 101 to 110 of about 11,240 (258)

Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba

bioRxiv, 2020
Naegleria fowleri is a pathogenic, thermophilic, free-living amoeba which causes primary amebic meningoencephalitis (PAM). Penetrating the olfactory mucosa, the brain-eating amoeba travels along the olfactory nerves, burrowing through the cribriform ...
Kayleigh Barrett, Logan M Tillery, J. Goldstein, Jared W. Lassner, Bram Osterhout, Nathan L. Tran, Lily Xu, R. Young, Justin Craig, Ian Chun, D. Dranow, J. Abendroth, S. Delker, D. Davies, S. Mayclin, B. Calhoun, M. Bolejack, B. Staker, S. Subramanian, I. Phan, D. Lorimer, P. Myler, T. Edwards, D. Kyle, C. Rice, James C. Morris, J. Leahy, Roman Manetsch, L. Barrett, Craig L. Smith, W. V. Van Voorhis   +30 more
semanticscholar   +1 more source

Seasonal Host Shifts for Legionella Within an Industrial Water‐Cooling System

Environmental Microbiology Reports, Volume 17, Issue 4, August 2025.
Taxonomic profiling for Legionella (the causative agent of Legionnaires' disease) and protist hosts within a water cooling tower showed seasonal peaks for Legionella that were associated with taxonomic shifts in the protist community. Legionella frequency was tracked using amplicon sequencing (blue line) and serogroup profiling (red line).
Suzanne Crull, Emlyn Hammer, Allison E. Mann, Lauren M. O'Connell, Ashlyn Soule, Elizabeth Griffith, Thomas Blouin, Robin L. Brigmon, Vincent P. Richards   +8 more
wiley   +1 more source

The susceptibility of pathogenic free-living amebae to chemotherapeutic agents : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]

, 1979
The treatment of infections caused by pathogenic free-living amebae (PFLA) has, until only recently, been far from successful. The continued screening of chemotherapeutic agents against amebae of the genera Naegleria and Acanthamoeba is therefore of the ...
Donald, Jennifer Jane
core  

Induced encystment improves resistance to preservation and storage of Acanthamoeba castellanii [PDF]

, 2008
Several conditions that allow the preservation, storage and rapid, efficient recovery of viable Acanthamoeba castellanii organisms were investigated. The viability of trophozoites (as determined by time to confluence) significantly declined over a period
Campbell, S. J., Henriquez, F. L., Ingram, P. R., Roberts, C. W.   +3 more
core   +1 more source

A systematic literature review and meta-analysis on the global prevalence of Naegleria spp. in water sources.

Transboundary and Emerging Diseases, 2020
Naegleria species (spp.) is a free-living amoebae whose pathogenic species such as N. fowleri pose a significant health risk to young people and the most important source of infection is water source.
R. Saberi, Z. Seifi, S. Dodangeh, Azar Najafi, Seyed Abdollah Hosseini, Davood Anvari, A. Taghipour, M. Norouzi, M. Niyyati   +8 more
semanticscholar   +1 more source

Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes

Molecular Microbiology, Volume 124, Issue 1, Page 54-65, July 2025.
This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Otmane Lamrabet, Raphael Munoz‐Ruiz, Imen Ayadi, Alixia Bourbon, Erwann Pain, Joseph Oddy, Pierre Cosson   +6 more
wiley   +1 more source

Nonpathogenic Free-Living Amoebae in Arkansas Recreational Waters [PDF]

, 1975
Selected recreational waters of Arkansas were sampled for pathogenic free-living limax amoebae. Water quality parameters were determined for correlation with amoebic population densities and species diversity.
Becker, David A., Bone, Leon W.
core   +2 more sources

Detection of protozoan hosts for Legionella pneumophila in engineered water systems by using a biofilm batch test [PDF]

, 2010
Legionella pneumophila proliferates in aquatic habitats within free-living protozoa, 17 species of which have been identified as hosts by using in vitro experiments. The present study aimed at identifying protozoan hosts for L.
Valster, R.M., Wullings, B.A., Kooij, D., van der   +2 more
core   +2 more sources

Agglutination of Naegleria fowleri and Naegleria gruberi by antibodies in human serum [PDF]

Journal of Clinical Microbiology, 1983
The capability of serum samples from 423 human subjects to agglutinate rounded cells of Naegleria fowleri nN68 was assessed. Sera from the umbilical cords of seven infants failed to agglutinate N. fowleri cells. The median agglutination titer was 1:4 for sera from children through age 4 years, 1:8 for sera from juveniles 5 to 15 years of age, and 1:16 ...
M F, Reilly, F, Marciano-Cabral, D W, Bradley, S G, Bradley   +3 more
openaire   +2 more sources

Laurinterol from Laurencia johnstonii eliminates Naegleria fowleri triggering PCD by inhibition of ATPases

Scientific Reports, 2020
Primary amoebic encephalitis (PAM) is a lethal disease caused by the opportunistic pathogen, Naegleria fowleri. This amoebic species is able to live freely in warm aquatic habitats and to infect children and young adults when they perform risk activities
Iñigo Arberas-Jiménez, Sara García-Davis, Aitor Rizo-Liendo, I. Sifaoui, M. Reyes-Batlle, Olfa Chiboub, R. Rodríguez-Expósito, A. Díaz-Marrero, J. Piñero, J. J. Fernández, J. Lorenzo-Morales   +10 more
semanticscholar   +1 more source