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Copper Metabolism in Naegleria gruberi and Its Deadly Relative Naegleria fowleri
Frontiers in Cell and Developmental Biology, 2022 Although copper is an essential nutrient crucial for many biological processes, an excessive concentration can be toxic and lead to cell death. The metabolism of this two-faced metal must be strictly regulated at the cell level. In this study, we investigated copper homeostasis in two related unicellular organisms: nonpathogenic Naegleria gruberi and ...
Robert Sutak +2 more
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Activation of complement by Naegleria
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1980Neither Naegleria nor its culture supernatant was found to be directly chemotactic for human neutrophils. Interaction of Naegleria with human serum, however, resulted in the generation of a strong chemotactic stimulus. The reduction of serum activity by heat-inactivation indicated a dependence on serum complement for the interaction.
B, Rowan-Kelly, A, Ferrante, Y H, Thong
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International Journal for Parasitology, 2011
The completion of the genome project for Naegleria gruberi provides a unique insight into the metabolic capacities of an organism, for which there is an almost complete lack of experimental data. The metabolism of Naegleria seems to be extremely versatile, as can be expected for a free-living amoeboflagellate, but although considered to be fully ...
Opperdoes, Fred R +2 more
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The completion of the genome project for Naegleria gruberi provides a unique insight into the metabolic capacities of an organism, for which there is an almost complete lack of experimental data. The metabolism of Naegleria seems to be extremely versatile, as can be expected for a free-living amoeboflagellate, but although considered to be fully ...
Opperdoes, Fred R +2 more
openaire +4 more sources
Naegleria fowleri meningoencephalitis
Blood, 2012![Figure][1] A 7-year-old boy with no prior illness or altered immunity presented to the emergency department with a 36-hour history of fever (103.7°F), emesis, headache, and lethargy. The patient had a history of swimming in a local lake the week before presentation.
Neslihan, Cetin, Douglas, Blackall
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Detection of Naegleria spp. and Naegleria fowleri: a comparison of flagellation tests, ELISA and PCR
Water Science and Technology, 2003 To detect Naegleria spp, in particular Naegleria fowleri, the causative agent of human primary amoebic meningoencephalitis, a flagellation test (FT) is routinely used followed by a specific ELISA. A positive FT indicates the presence of Naegleria spp although some false negatives are likely to occur since parameters for enflagellation vary greatly.
J, Behets +6 more
exaly +3 more sources
Cytopathogenicity of Naegleria fowleri and Naegleria gruberi for Established Mammalian Cell Cultures
The Journal of Parasitology, 1982Amebae of Naegleria fowleri and Naegleria gruberi were cytopathic for nine established mammalian cell cultures, including mouse and human fibroblasts, rabbit and monkey kidney cells, rat and mouse neuroblastoma cells, baby hamster kidney cells, and human epithelioma and carcinoma cells. Nine strains of N.
F M, Marciano-Cabral +3 more
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Naegleria and Acanthamoeba Infections: Review
Clinical Infectious Diseases, 1990Infections caused by small, free-living amebas are still unfamiliar to many clinicians, pathologists, and laboratorians. As of 31 July 1989, more than 140 cases of primary amebic meningoencephalitis caused by Naegleria fowleri and more than 40 cases of granulomatous amebic encephalitis caused by Acanthamoeba species (including two cases in patients ...
P, Ma +5 more
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