Results 61 to 70 of about 101,864 (307)
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Macherey-Nagel Product Catalog [PDF]
This commercial website from Macherey-Nagel features a database with references for nearly 3000 separation applications. The content is divided into chapters which are available for download in PDF format.
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Arthritis &Rheumatology, EarlyView.Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz +3 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Both susceptibility to, and severity of, rheumatoid arthritis (RA) is associated with the rs26232 C allele. Our primary aim was to identify the biologic mechanism underlying this association. Methods Expression of surrounding genes was compared among rs26232 genotypes.
Kevin J. Sheridan +12 more
wiley +1 more source
Le rôle d’Otto Nagel dans l’organisation de la Première Grande Exposition d’art allemand
Revue des études slavesThe First General German Art Exhibition in the USSR (1924-1925) was a significant cultural event organised with the active involvement of Otto Nagel, a self-taught German artist and member of the Communist Party. Nagel, as part of Künstlerhilfe, played a
Sergey Fofanov
doaj +1 more source
Fort Street Primary School at the top of Gallows Hill, Essex Street, Sydney, approximately 1890 / [PDF]
, 1890 Inscriptions: "Fort St. School, top of Gallows Hill, Essex St. ; Nagel photo"--Printed on card.; Condition: glued to card.; Also available online at: http://nla.gov.au/nla.pic ...
Nagel, Edward, active 1885-1895 photographer
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Arthritis &Rheumatology, EarlyView.Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes +10 more
wiley +1 more source
Kalagatos, 2017 Consciência; Problema mente-corpo; Lacuna explanatória; John Searle; Thomas ...
Tárik de Athayde Prata
doaj
Arthritis &Rheumatology, EarlyView.Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki +8 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen +13 more
wiley +1 more source