Results 181 to 190 of about 21,884 (244)

Global scientific research commons under the Nagoya Protocol: Towards a collaborative economy model for the sharing of basic research assets.

Environ Sci Policy, 2016
Dedeurwaerdere T, Melindi-Ghidi P, Broggiato A.   +2 more
europepmc   +1 more source

Adeno‐Associated Virus Vector‐Mediated Expression of Neuroligin 2 in the Mouse Hippocampus Attenuates the Progression of Pentylenetetrazol‐Induced Seizures

The Journal of Gene Medicine, Volume 28, Issue 10, October 2026.
Mice received bilateral hippocampal injections of an AAV vector expressing NL2, followed by repeated PTZ administration. NL2 expression in the HPC attenuated seizure progression and reduced c‐Fos expression in the ventral HPC. These findings suggest that AAV‐mediated NL2 expression in the HPC may be a potential therapeutic strategy for seizure control.
Tomohiro Tokutake, Akane Hara, Ayano Murayama, Yuto Mitsuda, Jun Yokose, Yusuke Yano, Yuki Shigetsura, Mika Ito, Naomi Takino, Shinichi Kumagai, Kuniko Shimazaki, Shin‐Ichi Muramatsu, Atsumi Nitta   +12 more
wiley   +1 more source

Clinical outcomes before and after the introduction of clazosentan in aneurysmal subarachnoid hemorrhage: a multicenter retrospective study of clipping and endovascular treatment. [PDF]

Neurosurg Rev
Takeuchi I, Muraoka S, Kinoshita F, Izumi T, Ishii K, Nishihori M, Goto S, Saito R, RECOVER Study Collaborators.   +8 more
europepmc   +1 more source

Electrogram Transition Patterns During Atrial Antitachycardia Pacing‐Mediated Termination [PDF]

J Arrhythm
Among 1,641 aATP‐terminated episodes in 38 patients, six electrogram transition patterns were identified. Irregular post‐aATP activity was the most common pattern preceding termination, regardless of pre‐aATP regularity (47% in regular and 63% in irregular pre‐aATP episodes). Episodes with irregular pre‐aATP activity took longer to terminate (median 13
Nakasuka K, Sakurai Y, Sekimoto S, Naganawa H, Mori K, Goto T, Suzuki T, Murakami Y, Seo Y.   +8 more
europepmc   +2 more sources

Expert Consensus Statement: Committee on Implantable Devices and Committee on Social Issues, Japanese Heart Rhythm Society (JHRS) Statement on Remote Monitoring of Cardiac Implantable Electronic Devices

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
This statement of the Japanese Heart Rhythm Society (JHRS) provides comprehensive guidance for medical professionals and device manufacturers involved in RM. ABSTRACT Remote monitoring (RM) has been established as a standard tool for the management of patients with cardiac implantable electronic devices (CIEDs), offering advantages such as early event ...
Eiichi Watanabe, Nobuhiro Nishii, Akiko Maeda, Yoshiro Sakai, Katsuhito Fujiu, Makoto Suzuki, Ritsushi Kato, Haruhiko Abe, Takashi Noda, Hiroshi Tada, Masahiko Takagi   +10 more
wiley   +1 more source

Smartphone-Based Remote Monitoring for Cardiac Implantable Electronic Devices: Transmission Performance and Early Alert Responsiveness. [PDF]

JACC Asia
Yanagisawa S, Inden Y, Hibino M, Sato Y, Narita Y, Miyazawa H, Miyamae K, Fukushima T, Hiramatsu T, Adachi K, Teraoka T, Ota R, Tanaka Y, Shimojo M, Tsuji Y, Okumura T, Murohara T.   +16 more
europepmc   +1 more source

Photon-counting detector CT vs energy-integrating detector CT for the diagnosis of arterial dissection in the cervicocerebral region: A single-center case series. [PDF]

Radiol Case Rep
Matsumoto K, Nakashima M, Kawai T, Kawaguchi T, Urano M, Kitera N, Watanabe S, Hiwatashi A.   +7 more
europepmc   +1 more source

Association between GLIM‐defined malnutrition and in‐hospital costs in adults with sepsis: A sub analysis of a prospective cohort study

Journal of Parenteral and Enteral Nutrition, Volume 50, Issue 7, Page 985-995, October 2026.
Abstract Background International statements suggest using the Global Leadership Initiative on Malnutrition (GLIM) criteria in intensive care units (ICUs); however, the economic impact of GLIM‐defined malnutrition in sepsis remains unclear. This study investigated the association between GLIM‐defined malnutrition and in‐hospital costs in sepsis ...
Yuki Hashimoto, Minoru Yoshida, Tomoka Miyagi, Akane Kariya, Hitomi Tanoue, Naoki Kanda, Yusuke Hoshi, Takahiro Fujita, Kensei Togo, Tomoaki Obata, Kenzo Ishii, Katsuyuki Abe, Chihiro Sato, Yoshifumi Heshiki, Daisetsu Yasumura, Shizuko Gomi, Masafumi Takahashi, Takashi Hongo, Keiji Sakurai, Miho Nishihara, Yuko Matsuda, Kiyota Chinen, Akiko Arai, Michihiro Maeda, Yuhei Irie, Hiroshi Kamijo, Kana Hosokawa, Daisuke Kasugai, Michiko Higashi, Ayaka Matsuoka, Hirotaka Ogawa, Yuichi Araki, Kenji Oike, Daigo Shimakura, Hajime Katsukawa, Toru Kotani, Takayuki Ogura, Keibun Liu, Kensuke Nakamura   +38 more
wiley   +1 more source

Beyond Blind Trust in Hospital Data Warehouses: Evaluating Real‐World Data Accountability

Learning Health Systems, Volume 10, Issue 4, October 2026.
ABSTRACT Introduction The reliability of real‐world evidence (RWE) depends on data accuracy and secondary users' ability to evaluate how data are generated and transformed. Although recent frameworks emphasize provenance, transparency, and auditability, their practical assessment in routine hospital settings remains unclear.
Akemi Morohashi, Satoshi Yamashita, Takahiro Imaizumi, Takuto Sano, Yachiyo Kuwatsuka, Masahiko Ando, Yoshimune Shiratori   +6 more
wiley   +1 more source

Clinical and Histopathological Evaluation of Maximal and Supramaximal Energy Direct Selective Laser Trabeculoplasty (DSLT): A Rabbit Model Safety Study

Lasers in Surgery and Medicine, Volume 58, Issue 8, Page 693-703, October 2026.
ABSTRACT Objectives This study aimed to assess the clinical and histopathological effects of maximal available and supramaximal energy exposure in direct selective laser trabeculoplasty (DSLT®) on target and nontarget ocular tissues compared with selective laser trabeculoplasty (SLT) and sham treatments.
Liat Mendel Veig, Zachary Sacks, Dorit Raz‐Prag, Abraham Nyska, Guy Kleinmann   +4 more
wiley   +1 more source