Results 41 to 50 of about 21,884 (244)

International Protection Policy of World Biological Diversity as the Factor of Sustainable Development of the Territorial Systems [PDF]

open access: yesE3S Web of Conferences, 2020
The article discusses the evolution of international biodiversity policy in the period from 1992 to 2019 as well as it demonstrates the significance of the global problem of species extinction and describes the structure and main directions of ...
Stepanov Anatoly   +3 more
doaj   +1 more source

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

open access: yesAdvanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko   +5 more
wiley   +1 more source

Protocoles bioculturels communautaires et travail-frontière : jeux de scripts autour des ressources génétiques à Madagascar

open access: yesSources, 2022
This article investigates the process of negotiating and drafting the Analavory farmers’ Biocultural Community Protocol (BCP) regarding access and benefit sharing of genetic resources and associated traditional knowledge.
Manohisoa Rakotondrabe, Fabien Girard
doaj   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin   +13 more
wiley   +1 more source

A Multicenter Randomized Phase II Trial Investigating the Effect of Polyglycolic Acid Sheet on the Prevention of Pancreatic Fistula After Gastrectomy with Prophylactic Lymph Node Dissection

open access: yesClinical and Experimental Gastroenterology, 2023
Dai Shimizu,1 Chie Tanaka,1 Mitsuro Kanda,1 Koki Nakanishi,1 Seiji Ito,2 Yachiyo Kuwatsuka,3 Masahiko Ando,3 Kenta Murotani,4 Michitaka Fujiwara,5 Yasuhiro Kodera1 1Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School
Shimizu D   +9 more
doaj  

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

open access: yesAdvanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao   +34 more
wiley   +1 more source

Implementation of Nagoya Protocol – the Case Study of Indonesia

open access: yesBangladesh Journal of Bioethics, 2020
Indonesia consists of more than 17,000 islands separated for hundreds of thousands of years, which consequently results in biodiversity and cultural diversity richness.
Endang Sukara   +2 more
doaj   +1 more source

Open Access and Data Sharing of Nucleotide Sequence Data

open access: yesData Science Journal, 2021
Open access, free access, and the public domain are different concepts. The International Nucleotide Sequence Database Collaboration (INSDC) permanently guarantees free and unrestricted access to nucleotide sequence data for all researchers, irrespective 
Masanori Arita
doaj   +1 more source

Interaction Between Operator and Assistant Certification Is Associated With Local Recurrence After Laparoscopic Rectal Cancer Surgery: An Ancillary Analysis of the EnSSURE Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
A significant synergistic interaction between operator and assistant certification was associated with a lower risk of local recurrence after laparoscopic rectal cancer surgery. Patients treated by both ESSQS‐qualified operators and assistants had the lowest risk of local recurrence, whereas a single qualification alone was not associated with a ...
Yusuke Sakimura   +114 more
wiley   +1 more source

The Nagoya Protocol and Customary Law: The Paradox of Narratives in the Law [PDF]

open access: yesLaw, Environment and Development Journal, 2013
The issue of protecting traditional knowledge and genetic resources is a textbook example of a legal problem in a world of hybrid legal spaces where a single problem, act or actor is regulated by multiple legal regimes. Unmistakingly, the Nagoya Protocol
Saskia Vermeylen
doaj  

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