Results 31 to 40 of about 160,730 (303)

Under-reported finding in acral erythema multiforme

open access: yesIndian Journal of Dermatology, 2015
Erythema multiforme is an acute muco-cutaneous hypersensitivity reaction with a variety of etiologies. It is characterized by a skin eruption, with or without oral or other mucous membrane lesions. General characteristics and treatmet have been described 
Adriana G Pena Romero   +2 more
doaj   +1 more source

Nail over nail technique for distal locking of femoral intramedullary nails [PDF]

open access: yesInternational Orthopaedics, 2008
The free hand technique remains the most popular method for distal locking; however, radiation exposure is a major concern. In an endeavour to overcome this concern, distal locking with the nail over nail technique is evaluated. Seventy patients with femoral diaphyseal fractures treated by intramedullary nailing were divided in two groups for distal ...
Rajesh, Rohilla   +5 more
openaire   +2 more sources

Nail consistency

open access: yes, 2005
The changes in brittle, friable nails are often confined to the surface of the nail plate; this occurs in superficial white onychomycosis and may be seen after the application of nail polish or base coat which causes ‘granulations’ in the nail keratin ...

core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Efficacy of Systemic Treatments of Nail Psoriasis: A Systemic Literature Review and Meta-Analysis

open access: yesFrontiers in Medicine, 2021
Importance: Nail involvement is a common condition in patients with psoriasis. The treatment of nail psoriasis is considered challenging and is often left untreated by physicians.Objective: To assess the efficacy of current systemic treatments on nail ...
Xuan Zhang, Bingbing Xie, Yanling He
doaj   +1 more source

Dermoscopy of Nail Psoriasis

open access: yes, 2014
Dermoscopy is a noninvasive and inexpensive method of magnifying in vivo examination of skin and nails allowing for immediate visualization of specific characteristics that could otherwise be overlooked by the naked eye.
Antonella Tosti   +3 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Results of midshaft clavicle fractures treated with expandable elastic and locking intramedullary nails

open access: yesActa Orthopaedica et Traumatologica Turcica, 2020
Objective: The aim of the study was to present the results of osteosynthesis with elastic expandable intramedullary nail for clavicle fractures. Methods: The study included 17 patients (11 males, 6 females; mean age 36.4 years, range: 21 to 54 years ...
Sinan Zehir, Turgut Akgul, Regayip Zehir
doaj   +1 more source

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