Results 31 to 40 of about 177,627 (251)

Toxicological Assessment of Key Substances in UV-Curable Nail Coatings: HEMA, TMPTA, TPO, HQ, and MEHQ

open access: yesMedžiagotyra
UV-curable nail coatings have gained widespread popularity due to their superior durability, gloss, and fast-curing properties. However, the use of (meth)acrylate monomers, photoinitiators, and inhibitors in these products raises concerns regarding ...
Zane GRIGALE-SOROCINA   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Nail trick

open access: yes, 2011
This activity proposes to balance 15 nails on the head of one nail. Nails can be balanced across the first nail if their weight is evenly distributed and if they can be stopped from slipping off.
Science Museum
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Nail trick

open access: yes, 2016
This activity proposes to balance 15 nails on the head of one nail. Nails can be balanced across the first nail if their weight is evenly distributed and if they can be stopped from slipping off.
Science Museum
core   +2 more sources

Nail manifestations in cancer chemotherapy: A cross-sectional study

open access: yesJournal of Dermatology and Dermatologic Surgery, 2020
Background: Anticancer chemotherapy is associated with multisystem adverse effects. Chemotherapy can affect skin, nails, and hair and may sometimes affect the quality of life to the point of requiring discontinuation of therapy.
Zainaba Mizaj   +5 more
doaj   +1 more source

The Exposure of Pb to Hair and Nails in Children Around “X” Coal Mines Using Atomic Absorption Spectroscopy (AAS) Method

open access: yesJurnal Kesehatan Lingkungan, 2021
Introduction: The exposure of Pb from coal mining activity could be accumulated primarily in the hair and nails. It was a presence as a bioindicator of Pb contamination in the community.
Tri Ana Mulyati   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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