Results 81 to 90 of about 429,618 (299)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Identification of semiparametric discrete outcome models with bounded covariates
, 2018 Identification of discrete outcome models is often established by using special covariates that have full support. This paper shows how these identification results can be extended to a large class of commonly used semiparametric discrete outcome models ...
Kashaev, Nail
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Functional resistance of enamel and the phenomenon of transtegumental fluid transport [PDF]
Саратовский научно-медицинский журнал, 2011 Current data related to transport of fluid through the covering tissue formations (skin, nail plate, dental enamel, gum valley) are being analyzed. A supposition is made of transtegumental fluid transport (TFT) as a general biological regularity which is
Okushko V.R. Okushko R.V. Ursan R.V.
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
How to perform the whole nail unit excision and grafting?
Turkderm Turkish Archives of Dermatology and Venereology, 2023 Ozan Erdem +3 more
doaj +1 more source
Non-interacting gravity waves on the surface of a deep fluid
, 2019 We study the interaction of gravity waves on the surface of an infinitely deep ideal fluid. Starting from Zakharov's variational formulation for water waves we derive an expansion of the Hamiltonian to an arbitrary order, in a manner that avoids a ...
Ussembayev, Nail S.
core
REDUKSI ION MERKURI DALAM LIMBAH CAIR PENAMBANGAN TRADISIONAL DENGAN MENGGUNAKAN BOTTOM ASH BONE COAL [PDF]
, 2018 Merkuri (Hg) merupakan salah satu logam berat yang banyak dipakai dalam proses ekstraksi emas pada tambang rakyat. Pembuangan limbah merkuri hasil pengolahan emas ini dapat menjadi masalah bagi lingkungan jika tidak di tangani terlebih dahulu. Penelitian
Nail
core
, 2014 Objective: The authors present the first clinical results in treatment of calcaneal fractures using a newly developed calcaneal nail (C-NAIL). In their presentation the authors describe the clinical study, the indication for the minimal-invasive operation and explain in detail the surgical procedure[for full text, please go to the a.m. URL]
Pompach, M +4 more
openaire +2 more sources