Results 81 to 90 of about 182,145 (299)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

How to perform the whole nail unit excision and grafting?

open access: yesTurkderm Turkish Archives of Dermatology and Venereology, 2023
Ozan Erdem   +3 more
doaj   +1 more source

Nail plate and soft tissue abnormalities

open access: yes, 2003
Onycholysis refers to the detachment of the nail from its bed at its distal and/or lateral attachments (Figure 4.1). The pattern of separation of the plate from the nail bed takes many forms.

core   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Surgical anatomy of the nail apparatus.

open access: yes, 2006
Contains fulltext : 49712.pdf (Publisher’s version ) (Closed access)Nail surgery is an integral part of dermatologic surgery. An in-depth knowledge of the anatomy, biology, physiology, and gross pathology of the entire nail unit is ...
Haneke, E., Haneke, Eckart
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Functional resistance of enamel and the phenomenon of transtegumental fluid transport [PDF]

open access: yesСаратовский научно-медицинский журнал, 2011
Current data related to transport of fluid through the covering tissue formations (skin, nail plate, dental enamel, gum valley) are being analyzed. A supposition is made of transtegumental fluid transport (TFT) as a general biological regularity which is
Okushko V.R. Okushko R.V. Ursan R.V.
doaj  

Advanced nail surgery [PDF]

open access: yes, 2011
Six techniques not yet widely known or used in the dermatologic surgery of the nails are briefly described. Small-to-medium-sized tumours of the proximal nail fold (PNF) can be excised and the defect repaired with advancement or rotation flaps.
Haneke, Eckart, Haneke, E, Haneke E
core   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

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