Results 61 to 70 of about 429,618 (299)

Evaluation of the ability of a novel miconazole formulation to penetrate nail by using three in vitro nail models [PDF]

open access: yes, 2017
This document is the Accepted Manuscript of the following article: Luisa Christensen, Rob Turner, Sean Weaver, Francesco Caserta, Lisa Long, Mahmoud Ghannoum, and Marc Brown, ‘Evaluation of the Ability of a Novel Miconazole Formulation To Penetrate Nail ...
Bodman   +12 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Stability of a granular layer on an inclined "fakir plane" [PDF]

open access: yes, 2012
We present here experimental results on the effect of a forest of cylinder obstacles (nails) on the stability of a granular layer over a rough incline, in a so-called "fakir plane" configuration.
Benito, Jesica   +3 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Natural expulsion of a sharp iron nail: Right main bronchus to the alimentary tract: A case report

open access: yesClinical Case Reports, 2021
A young girl inhaled a pointed iron nail into the right main bronchus. However, both rigid bronchoscopy and oesophagoscopy failed to locate the nail. Surprisingly, it was detected in the abdomen by C‐arm and was expelled uneventfully while defecating two
Prasanta Poudyal   +4 more
doaj   +1 more source

Clinical, histological and prognostic features of a novel nail-bed lesion of cats: 41 cases [PDF]

open access: yes, 2017
There is a distinct subset of lesions arising on the digits of cats, located at or close to the nail-bed epithelium, which are typically composed of proliferative fibroblast-like cells, multinucleate giant cells and areas of osseous metaplasia, but ...
Dobromylskyj, M J   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

THE USE OF THE PROXIMAL FEMORAL NAIL IN THE TREATMENT OF PROXIMAL FEMUR FRACTURES IN THE OLD PATIENTS

open access: yesTravmatologiâ i Ortopediâ Rossii, 2016
The analysis of results of surgical treatment of 157 patients with proximal femur fractures was presented. In all cases the osteosynthesis using fixator PFN was performed in clinic of traumatology amd orthopedics of Moscow Municipal Hospital N 71 from ...
V. N. Borovkov   +2 more
doaj   +1 more source

The Casimir-Polder effect for a stack of conductive planes

open access: yes, 2016
The Casimir-Polder interaction between an atom and a multilayered system composed of infinitely thin planes is considered using the zeta-function regularization approach with summation of the zero-point energies.
Kashapov, Rashid   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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