Results 61 to 70 of about 182,145 (299)

Nail trick

open access: yes, 2016
This activity proposes to balance 15 nails on the head of one nail. Nails can be balanced across the first nail if their weight is evenly distributed and if they can be stopped from slipping off.
Science Museum
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Topical Delivery of Calcium Silicate for Nail Health: A Clinical and Experimental Evaluation

open access: yesCosmetics
Silicon (Si) plays a crucial role in maintaining the structural integrity of nails, skin, and hair by supporting collagen synthesis and keratin stability. Despite its recognized benefits, effective topical delivery methods remain underexplored.
Viktoria Engqvist, Håkan Engqvist
doaj   +1 more source

Diagnostic Concordance in Tertiary (Dermatologists-to-Experts) Teledermoscopy: A Final Diagnosis-Based Study on 290 Cases

open access: yesDermatology Practical & Conceptual, 2020
Background: Teledermoscopy (TDS) improves diagnostic accuracy and decreases the number of unnecessary consultations. Objectives: To determine the diagnostic concordance in tertiary (dermatologist-to-experts) TDS with histopathology/follow-up–based ...
Anne Marchetti   +8 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Distal Femur Fractures: Nail, Plate or Both? A Systematic Review

open access: yesApplied Sciences
Background: Distal femur fractures remain among the most challenging injuries in orthopedic trauma, particularly in elderly or osteoporotic patients and in cases involving periprosthetic or highly comminuted distal femur fracture patterns.
Marco Barbaliscia   +10 more
doaj   +1 more source

THE USE OF THE PROXIMAL FEMORAL NAIL IN THE TREATMENT OF PROXIMAL FEMUR FRACTURES IN THE OLD PATIENTS

open access: yesTravmatologiâ i Ortopediâ Rossii, 2016
The analysis of results of surgical treatment of 157 patients with proximal femur fractures was presented. In all cases the osteosynthesis using fixator PFN was performed in clinic of traumatology amd orthopedics of Moscow Municipal Hospital N 71 from ...
V. N. Borovkov   +2 more
doaj   +1 more source

A finite element strategy applied to intramedullary nailing of the proximal femur [PDF]

open access: yes, 2005
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.An intramedullary nail is a trauma treatment device used for fracture fixation of long bones. These devices are subject to failure, including lag screw
Simpson, David John
core   +4 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Dramatic response of cutaneous, nail, and joint symptoms of psoriasis to apremilast

open access: yesClinical Dermatology Review, 2019
Apremilast has been available in India for the past 6 months as a therapy for psoriasis. A 31-year-old male patient with a diagnosis of psoriasis with oligoarthritis who was not tolerating methotrexate was treated with apremilast.
Meghana Bathina   +3 more
doaj   +1 more source

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