Gaps in Documentation of Psoriatic Domains in General Rheumatologic Practices Compared to Rheumatology-Dermatology Combined Clinics. [PDF]
Rice AL+7 more
europepmc +1 more source
Dermoscopic findings of psoriatic nail and their relationship with disease severity
Ayşegül Polat, Yelda Kapıcıoğlu
openalex +1 more source
CRISPR/Cas9 screening reveals PTPN2 as essential for ALK+ ALCL survival. PTPN2 regulates TFRC to promote PINK1‐PRKN mitophagy. Oral PTPN2 inhibitor ABBV‐CLS‐484 disrupts mitochondrial renewal and blocks TFRC‐mediated mitophagy to exert anti‐tumor activities, supporting clinical development for ALK+ ALCL.
Wei‐Ting Wang+11 more
wiley +1 more source
Deceptive digits: squamous cell carcinoma of the nail bed masquerading as glomus tumor. [PDF]
Maheshwari N+3 more
europepmc +1 more source
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma+18 more
wiley +1 more source
Dermoscopy-aided diagnosis of uncommon onychauxis in a 21-year-old: A case report and review of the literature. [PDF]
Pham GM, Pham RN.
europepmc +1 more source
piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang+16 more
wiley +1 more source
Dermatology (Beau's Lines) and Forensic Pathology (Harris Lines and Linear Enamel Hypoplasia) Signs of Growth Arrest: A Case Report and Literature Review. [PDF]
Cohen PR.
europepmc +1 more source
DARIER'S DISEASE OF MODERATE SEVERITY WITH MUCOSALAND NAIL INVOLVEMENT
Soumya Agarwal, Nishant Singh
openalex +1 more source