Results 221 to 230 of about 54,810 (302)

Atypical fingernail onychomycosis due to Aspergillus niger in a healthy adult: an unusual presentation of a non-dermatophyte mold infection. [PDF]

BMC Infect Dis
Jawade SA, Bankar NJ, Singh SP, Quazi ST, Dudhe MS, Khandeshe R.   +5 more
europepmc   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Nail structural alterations and zinc levels in the elderly: an observational cross-sectional study. [PDF]

PeerJ
Yusharyahya SN, Chu CY, Krisanti RIA, Legiawati L, Astriningrum R, Moelyono LA, Betavani VMP, Japranata VV.   +7 more
europepmc   +1 more source

Rewiring NADH Metabolism Through NQO1‐Mediated Redox Cycling for Targeted Follicular Lymphoma Therapy

Advanced Science, EarlyView.
ABSTRACT Follicular lymphoma (FL) remains an incurable B‐cell malignancy with high relapse rates, and conventional therapies are often limited by significant toxicity, highlighting the need for novel treatments. We identified that FL exhibits markedly low expression of NAD(P)H: quinone oxidoreductase 1 (NQO1), a key enzyme required for activating ...
Jinxing Zhang, Ziqi Wang, Ye Weng, Yulin Fu, Yuelong Jiang, Beilin Zhuang, Wenzi Zeng, Xiangchun Zhang, Bing Xu, Jie Zha, Hongjun Zhuang   +10 more
wiley   +1 more source

Is Hyperkeratosis of the First and Fifth Toenails a Neuropathic Manifestation Associated with L5-S1 Nerve Root Compression? A Case Series. [PDF]

Skin Appendage Disord
Aydogdu CT, Yilmaz O, Kendir M, Aydogdu O.   +3 more
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Artificial Intelligence Meets Nail Diagnostics: Emerging Image-Based Sensing Platforms for Non-Invasive Disease Detection. [PDF]

Bioengineering (Basel)
Marode TP, Bhangdiya VK, Nemane S, Tulaskar D, Sarad VM, Sankar K, Chopade S, Avthankar A, Bhaiyya M, Kulkarni MB.   +9 more
europepmc   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Nail Amino Acid and Trace Element Profiles and Their Association with Clinical Severity in Nail Psoriasis. [PDF]

Clin Cosmet Investig Dermatol
Özen T, Gürel MS, Erdem O, Özçelik D, Pastacı Özsobacı N, Selek Ş, Köktaşoğlu F.   +6 more
europepmc   +1 more source