Results 141 to 150 of about 133,063 (223)

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair. [PDF]

Bone Res
Kang H, Strong AL, Sun Y, Guo L, Juan C, Bancroft AC, Choi JH, Pagani CA, Fernandes AA, Woodard M, Lee J, Ramesh S, James AW, Hudson D, Dalby KN, Xu L, Tower RJ, Levi B.   +17 more
europepmc   +1 more source

Validation of the ABILHAND questionnaire as a measure of manual ability in patients with rheumatoid arthritis. [PDF]

Ann Rheum Dis, 2007
Durez P, Fraselle V, Houssiau F, Thonnard JL, Nielens H, Penta M.   +5 more
europepmc   +1 more source

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

Advanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu, Lin Jing, Yixin Li, Jinxing Zhou, Xiaohui Cui, Sen Li, Shijie Yang, Fangming Kan, Junfeng Du, Wentao Zhong, Sheng Yu, Ning Wang, Xing Jia, Junhui Li, Pan Nie, Zhenzhong Chen, Ying Han, Lingxi Jiang, Xiyun Yan, Hongxia Duan, Baiyong Shen   +20 more
wiley   +1 more source

Automated 3D multi-color single-molecule localization microscopy

, 2023
Power RM, Tschanz A, Zimmermann T, Ries J.   +3 more
europepmc   +1 more source

Digit mechanics in relation to endpoint compliance during precision pinch. [PDF]

J Biomech, 2015
Nataraj R, Audu ML, Li ZM.
europepmc   +1 more source

RAB5A Promotes Active Fluid Wetting by Reprogramming Breast Cancer Spheroid Mechanics

Advanced Science, EarlyView.
RAB5A‐mediated unjamming enhances active wetting through distinct biomechanical processes: a) upregulation of specific integrin subunits, enhanced focal adhesions kinetics and activity; b) supracellular organization relying on nanoscale integrin clustering, and the formation of a stiff and collective actin cable; and c) softening of the spheroid core ...
Grégoire Lemahieu, Paulina Moreno‐Layseca, Tobias Hub, Carlo Bevilacqua, Manuel Gómez‐González, Federica Pennarola, Federico Colombo, Andrew E. Massey, Leonardo Barzaghi, Andrea Palamidessi, Leon‐Luca Homagk, Samuel F. H. Barnett, Alexander X. Cartagena‐Rivera, Christine Selhuber‐Unkel, Robert Prevedel, Xavier Trepat, Joachim P. Spatz, Johanna Ivaska, Giorgio Scita, Elisabetta Ada Cavalcanti‐Adam   +19 more
wiley   +1 more source

WHEN AND WHY DO HEDGEHOGS AND FOXES DIFFER? [PDF]

Crit Rev (N Y), 2010
Keil FC.
europepmc   +1 more source

Controlling Release Kinetics of an Adjuvant from a Depot Improves the Efficacy of Local Immunotherapy in Metastatic Cancer

Advanced Science, EarlyView.
We show that intratumoral release of an immunotherapy—CpG —can be tuned with molecular precision by complexing it to an elastin‐like polypeptide (ELP). Injecting ELP‐CpG and an excipient ELP into tumors drives thermally‐triggered phase separation into a micro‐scale “sponge” depot that releases CpG at rates depending on the ELP composition, which ...
Joshua J. Milligan, Rachel L. Strader, Arunangshu Chakrabarty, Max Ney, Parul Sirohi, Jonathan C. Su, Anastasia K. Varanko, Yulia Shmidov, Kalina Tsolova, Cassio Mendes Fontes, Anna Finkelstein, Rohinee Mattikalli, Yun‐Xing Wang, Lixin Fan, Xinghai Li, Smita K. Nair, Ashutosh Chilkoti   +16 more
wiley   +1 more source

On the way to total integration of prosthetic pylon with residuum. [PDF]

J Rehabil Res Dev, 2009
Pitkin M.
europepmc   +1 more source

Enhanced Brain‐Heart Connectivity as a Precursor of Reduced State Anxiety after Therapeutic Virtual Reality Immersion

Advanced Science, EarlyView.
This study shows that enhanced brain‐to‐heart coupling is a precursor of anxiety reduction following a virtual reality‐based non‐pharmacological intervention. Driven by midline beta rhythms, this effect suggests the involvement of central‐autonomic interactions.
Idil Sezer, Paul Moreau, Mohamad El Sayed Hussein Jomaa, Valérie Godefroy, Bénédicte Batrancourt, Richard Lévy, Anton Filipchuk   +6 more
wiley   +1 more source