Results 21 to 30 of about 3,079 (260)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Seismic Performance of Anchored Brick Veneer [PDF]
, 2009 A study was conducted on the out-of-plane seismic performance of anchored brick veneer with wood-frame backup wall systems, to evaluate prescriptive design requirements and current construction practices.
LaFave, James M. +1 more
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Test Excavations at the Spanish Governor\u27s Palace, San Antonio, Texas [PDF]
, 1997 Test excavations were carried out in October 1996 by the Center for Archaeological Research of The University of Texas at San Antonio in front of the Spanish Governor\u27s Palace in Military Plaza in downtown San Antonio.
Fox, Anne A.
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Defining appropriate limit states for design of timber connections in Australia and New Zealand [PDF]
, 2007 Both Australia and New Zealand design standards for timber structures are in limit states format, but these are first generation soft conversions of previous working stress design standards. It is anticipated that development of a new combined Australian
Crews, K
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Multi–scale modelling of timber–frame structures under seismic loads [PDF]
, 2013 This paper introduces a versatile hysteretic constitutive law, developed for various joints with steel fasteners commonly used in timber structures (nails, screws, staples, 3D connectors of bracket type, punched plates). Compared to previous
Baroth, Juliene +3 more
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Historic Archeological Investigations at Roberts Cemetery Near Troy, Bell County, Texas [PDF]
, 2014 A preliminary archeological investigation was conducted in 2008 at Roberts Cemetery near Troy, Texas, as part of the Texas Department of Transportation’s planned expansion of Interstate Highway 35.
Abbott, James T. +5 more
core +2 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Easily Implantable and Stable Nail-Fastener for Skeletal Fixation and Method [PDF]
, 2012 An intramedullary nail (20) for insertion into the medullary canal (26) in a bone (24) surrounded by the cortex (28) and defines a bore (34) extending transverse to the intramedullary nail (20).
Atkinson, Patrick, LeCronier, David
core +1 more source