Results 41 to 50 of about 135,032 (257)

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

open access: yesFEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee   +5 more
wiley   +1 more source

Patient Perceptions of Medication Therapy for Prevention of Posttraumatic Osteoarthritis Following Anterior Cruciate Ligament Injury: A Qualitative Content Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Posttraumatic osteoarthritis (PTOA) accounts for nearly 12% of osteoarthritis incidences and often occurs after anterior cruciate ligament (ACL) tear. Ensuring the uptake of preventive treatments for PTOA requires that investigators and clinicians understand factors influencing patients to seek preventive therapies.
Lily M. Waddell   +10 more
wiley   +1 more source

Wearable Haptic Feedback Interfaces for Augmenting Human Touch

open access: yesAdvanced Functional Materials, EarlyView.
The wearable haptic feedback interfaces enhance user experience in gaming, social media, biomedical instrumentation, and robotics by generating tactile sensations. This review discusses and categorizes current haptic feedback interfaces into force, thermal, and electrotactile stimulation‐based haptic feedback interfaces, elucidating their current ...
Shubham Patel   +3 more
wiley   +1 more source

Multi–scale modelling of timber–frame structures under seismic loads [PDF]

open access: yes, 2013
This paper introduces a versatile hysteretic constitutive law, developed for various joints with steel fasteners commonly used in timber structures (nails, screws, staples, 3D connectors of bracket type, punched plates). Compared to previous
Baroth, Juliene   +3 more
core  

Material Composition Gradient Controls the Autonomous Opening of Banksia Seed Pods in Fire‐Prone Habitats

open access: yesAdvanced Functional Materials, EarlyView.
The seed pod valves of Australian Banksia attenuata plants are not simply bi‐layers which bend when dry. These experiments and models reveal complex mechanics, which allow seed release only after several steps of seed pod opening. Stiffness gradients prevent delamination of the valves during loading, and a shape‐memory function protects the seeds ...
Friedrich Reppe   +7 more
wiley   +1 more source

All‐Cellulose‐Based Photonic Glitters

open access: yesAdvanced Functional Materials, EarlyView.
Uniform, disc‐shaped photonic CNC glitters with adjustable structural colors and diameters are fabricated on hydrophilic ethyl cellulose films using electrospray deposition. By employing patterned ethyl cellulose films with pre‐designed hydrophilic regions, photonic patterns can be created with these all‐cellulose‐based glitters, demonstrating their ...
Ting Wang   +5 more
wiley   +1 more source

Reliability Indices for Bolted and Nailed Connections in Wood Structures

open access: yes, 2001
Recently published test data for bolted and nailed connections was evaluated to assess the structural reliability inherent in current allowable stress design procedures for connections in wood structures.
Bender, Donald A, Pollock, David
core   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi   +6 more
wiley   +1 more source

Cyclic Testing of Reinforced Earthbag Walls [PDF]

open access: yes, 2018
Earthen construction is the most popular building method around the world. One particular building method, using earthbags, has shown promise in performing well against seismic activity. This project undertook the goal of developing a preliminary seismic
Darby, Taylor   +2 more
core   +1 more source

A hysteresis model for timber joints with dowel-type fasteners [PDF]

open access: yes, 2018
Predicting the mechanical behaviour and the failure mechanism of timber joints with dowel-type fasteners re- quires consideration of several factors, including the geometrical and mechanical properties of the metal fas- tener, the physical properties of ...
Fragiacomo, Massimo   +3 more
core   +1 more source

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