Results 71 to 80 of about 3,079 (260)

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang, Jihana Achour, Laila Emam, Younes Louaguenouni, Catherine Cailleau, Françoise Mercier‐Nomé, Séverine Domenichini, Claudine Delomenie, Sezen Gul, Juliette Vergnaud, Nicolas Tsapis, Arnaud Mansart, Djillali Annane, Francois Fay, Elias Fattal   +14 more
wiley   +1 more source

Lateral Gradual Opening Osteotomy of the Tibia With Monolateral External Fixator for Correcting the Valgus Deformity of the Tibia. [PDF]

Arthrosc Tech, 2022
Motta DPD, Faria JLR, Cruz CM, Aguiar DP, Amaral MVG, Kropf LL, Motta GATAD, Cerqueira FDS, Leonetti BD, Cerqueira FDS.   +9 more
europepmc   +1 more source

Innovative shot nails fastening for bonded steel plates strengthening concrete structures: A comparative research with conventional chemical anchor

Case Studies in Construction Materials
As an alternative to chemical bolt fasteners for bonded steel plate strengthening, shooting nails have the advantages of higher efficiency and lower damage to existing concrete structures. In this paper, through interfacial single-shear tests, a comparative investigation on the shear capacity of different steel-concrete interfaces, including shooting ...
Haoyu Liu, Mingxue Xu, Hongbing Chen, Xiaogang Liu   +3 more
openaire   +2 more sources

Effect of 2D and 3D ECM and Biomechanical Cues on Human iPSC‐Derived Liver Progenitor Cell Differentiation

Advanced Healthcare Materials, EarlyView.
An engineered microtissue model is developed and optimized to investigate human liver development. Extracellular matrix composition and mechanical forces are tuned using high‐throughput assays. Human induced pluripotent stem cells serve as the cellular source, enabling the observation of de novo patterned differentiation.
Ishita Jain, Brock Grenci, Hyeon Ryoo, Yang Yuan, Salman R. Khetani, Gregory H. Underhill   +5 more
wiley   +1 more source

A New Concept of Using Femoral Condyles Surface for Femoral Component Alignment During Total Knee Arthroplasty: A Technical Note. [PDF]

Indian J Orthop, 2023
Sarzaeem MM, Amouzadeh F, Salehi B, Movahedinia M, Soleimani M.   +4 more
europepmc   +1 more source

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

24th National Timber Bridge Design Competition [PDF]

, 2016
For the 2016 Senior Design project, our team elected to design and construct a short-span pedestrian bridge for the 24th National Timber Bridge Design Competition.
McNamara, Marie, Porter, Andrew D., Sbicca, Sarah Martina   +2 more
core   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Numerical and Experimental Analysis of the Rotational Stiffness of a Timber Semi-Rigid Dowel-Type Connection. [PDF]

Materials (Basel), 2022
Johanides M, Lokaj A, Dobes P, Mikolasek D.   +3 more
europepmc   +1 more source

Development and testing of shingle-type solar cell molecules [PDF]

The details of a shingle module design which produces in excess of 97 watts/sq m of module area at 1 kW/sq m insolation and at 60 C are reported. This selected design employs a tempered glass coverplate to provide the primary solar cell structural ...
Shepard, N. F.
core   +1 more source