Results 151 to 160 of about 236,152 (278)

Methotrexate Toxicity in a Patient With Renal Failure Despite a Normal Methotrexate Concentration: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra, Mahshad Ghoddusi, Mahsa Mottahedi, Maryam Albaji, Samira Kafan, Roya Saedpanah, Amir Shokri, Elham Nazar   +7 more
wiley   +1 more source

Vitamin D receptor signaling in inflammatory senescence–associated skin aging: Mechanisms and therapeutic potentials

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Vitamin D receptor (VDR) signaling is implicated in inflammatory senescence‐associated skin aging, a growing health concern in aging populations where cellular senescence and chronic inflammation converge to create complex pathophysiological conditions.
Liancheng Guan, Fan Yang, Meijuan Li, Yujia Chen, Zexin Zhao, Hongxia Li, Deping Luo, Qian Li, Yunzhi Chen   +8 more
wiley   +1 more source

Study Of Nail Changes In Psoriasis

Indian Journal of Dermatology, 2004
Background: In psoriasis, nail involvement is quite a common phenomenon and the manifestation may range from pitting, Beau’s line, leuconychia, onychorrhexis, onycholysis, subungual hyperkeratosis, thinning of nail plate to less commonly ...
Ghosal Astikmoni, Gangopadhyay D N, Chanda M, Das Nilay Kanti   +3 more
doaj  

Ultrasonography reveals nail thickening in patients with chronic plaque psoriasis.

, 2012
Nail psoriasis is usually investigated anddiagnosed by clinical examination. Ultrasonography is anon-invasive imaging technique for studying soft tissueinvolvement.
GIROLOMONI, Giampiero, GISONDI, Paolo, IDOLAZZI, Luca   +2 more
core   +1 more source

A Systematic Review of Literature: TNF‐α Blockers and JAK Inhibitors for the Treatment of Stevens‐Johnson Syndrome, Toxic Epidermal Necrolysis, and Severe Forms of Erythema Multiforme

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Stevens‐Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and erythema multiforme major (EM major) are severe dermatologic conditions characterized by varying degrees of skin detachment and involvement of mucosal membranes, often triggered by drug reactions or infections.
Sadaf Salehi, Pooneh Torabi, Mahsa Abbaspour, Nima Hajizadeh, Sara Sadeghi, Alireza Jafarzadeh, Azadeh Goodarzi   +6 more
wiley   +1 more source

‘I Didn't Know, I Definitely Guessed.’ Exploring Pre‐Registration Podiatry Students' Approach to Identifying Dermatological Conditions in Different Skin Tones, a Mixed Methods Study

Journal of Foot and Ankle Research, Volume 19, Issue 2, June 2026.
ABSTRACT Background Research suggests that healthcare professionals find it more difficult to correctly diagnose dermatological conditions in the nonwhite patient demographic. People of colour experience higher rates of delayed and misdiagnosis, contributing to an increased mortality risk and increased health inequalities that remain widespread ...
Simon Otter, Faye Funnell, Alex Sykes, Kerry Ewins‐Strowger, Nadine Hemming, Deborah Whitham   +5 more
wiley   +1 more source

Methods of Outcomes Measurement in Nail Psoriasis

, 2013
Background: Nail involvement is a common feature of psoriasis, predicting higher disease severity and greater impairment in quality of life. Valid assessment of nail psoriasis is relevant for research and routine clinical use.
Ogilvie, Alexandra, Augustin, Matthias
core  

Patient Characteristics, Disease Profile and Treatment Patterns in Mild and Moderate Psoriasis Patients: Results From Real‐World Clinical Practices in Five European Countries (PROSPECT Study)

JEADV Clinical Practice, Volume 5, Issue 2, Page 517-528, June 2026.
ABSTRACT Background Categorisation of psoriasis (PsO) disease severity in patients varies, although body surface area (BSA) affected is commonly used (< 3% ‘mild’, 3%–10% ‘moderate’ and > 10% ‘severe’). While moderate‐severe PsO has been well‐studied, more limited information regarding mild‐to‐moderate PsO is available.
Emily Goddard, Aaron Keal, James Hetherington, Sophie Barlow, David Wu, Melany Worbes‐Cerezo, Alexander Litvintchouk   +6 more
wiley   +1 more source

Psychological aspects of Psoriasis [PDF]

, 1992
Psoriasis is a skin condition characterised by raised, red, scaling patches that cover the body to varying degrees, with a prevalence of 1-3% in Caucasian populations. There is evidence that sufferers hospitalised for treatment of then psoriasis are more
Dooley, Gordon
core  

Serum and Fecal Calprotectin Levels Do Not Alter Significantly in Patients With Psoriasis Switching to Brodalumab After Loss of Effect From TNF‐α Inhibitors

JEADV Clinical Practice, Volume 5, Issue 2, Page 615-619, June 2026.
ABSTRACT Background Psoriasis is a chronic inflammatory skin disease often associated with systemic conditions like psoriatic arthritis and inflammatory bowel disease (IBD). Calprotectin, an inflammatory biomarker commonly used in IBD, has also been found elevated in psoriasis.
Admir Vižlin, Hans‐Peter Claesson, Ylva Andersch Björkman, Martin Gillstedt, Eva Klingberg, Emanuela Micu, Amra Osmančević   +6 more
wiley   +1 more source