Results 51 to 60 of about 8,863 (150)

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Systemic Treatment of Psoriasis: Current Evidence on Efficacy and Safety

The Journal of Dermatology, EarlyView.
ABSTRACT Systemic treatments for moderate‐to‐severe plaque psoriasis have been advanced from broad immunosuppressants up to agents more selectively targeting cytokines, cytokine receptors, or intracellular signaling. The current systemic treatments mainly consist of conventional systemic agents, biologics targeting tumor necrosis factor (TNF)‐α ...
Teppei Hagino, Naoko Kanda
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Nail Abnormalities in Thai Psoriasis Patients with Disease Severity and Impact on Quality of Life

Siriraj Medical Journal, 2014
Background: Nail abnormalities are common in psoriasis. The relationship between nail abnormalities and disease severity or impact on quality of life has scarcely been reported. Objectives: The aims of this study were to find the proportion and types of
Sukhum Jiamton, Rujee Phuardchantuk, Chanisada Wongpraparut, Leena Chularojmontri, Narumol Silpa-archa, Pranee Kasemsarn, Kanokvalai Kulthanan, Puan Suthipinittharm   +7 more
doaj  

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Temporary transfer tattoos and their use in student teaching in dermatology ‐ a monocentric observational study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background The teaching of elementary skin lesions and the ABCDE rule are central components of undergraduate medical education in dermatology. This content is typically taught using photographs, moulages, or patient examples. Independent practice under supervision, however, is often difficult to implement in everyday clinical work ...
Conrad Hempel, Franziska Jochims, Jan‐Christoph Simon, Daisy Rotzoll   +3 more
wiley   +1 more source

Nail psoriasis as a severity indicator: results from the PsoReal study

Patient Related Outcome Measures, 2010
Marc A Radtke1, Anna K Langenbruch1, I Schäfer1, Katharina Herberger1, Kristian Reich2, Matthias Augustin11Institute for Health Services Research in Dermatology and Nursing, University Medical Center of Hamburg-Eppendorf, Hamburg ...
I Schäfer, Anna K Langenbruch, Marc A Radtke, et al   +3 more
doaj  

PeakPASI as a marker of maximum psoriasis severity: a single‐center, cross‐sectional retrospective and questionnaire‐based study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background The Psoriasis Area and Severity Index (PASI) is the standard measure for psoriasis severity but reflects only a single time point and may underestimate long‐term disease burden. To assess whether the highest‐ever recorded PASI (PeakPASI) can serve as a marker of historical disease severity and correlate with treatment burden and ...
Simran Wilkhoo, Stefanie Ziehfreund, Enya Müller, Hanna Wecker, Stefanie Eyerich, Tilo Biedermann, Alexander Zink   +6 more
wiley   +1 more source

Ultrasonographic characterization of the nails in patients with psoriasis and onychomycosis

The Egyptian Journal of Radiology and Nuclear Medicine, 2015
Objective: The study aimed at assessment of ultrasound (US) in diagnosing nail psoriasis and onychomycosis. Methods: One hundred subjects were included: the psoriatic patients group (n = 25), the onychomycosis patients group (n = 25) and the control ...
Shaymaa Muhammad Ally Essayed, Mohammad Ahmad al-Shatouri, Yasser Salem Nasr Allah, Mona Ahmad Atwa   +3 more
doaj   +1 more source

Onychogryposis Secondary to Underlying Phalangeal Non‐Union

JEADV Clinical Practice, EarlyView.
Sunil Jaiswal, Shraddha Uprety, Pratichya Thapa, Smarika Upadhyaya, Aditi Joshi, Prakriti Lamichhane   +5 more
wiley   +1 more source