Results 81 to 90 of about 236,152 (278)

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, Accepted Article.
Background Type I interferonopathies are heterogeneous diseases driven by dysregulated IFN‐I signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. Objective To characterize the clinical, immunological, genetic, molecular profiles of patients with suspected enhanced IFN‐I signaling, and assess ...
Ismail Yaz, Seza Ozen, Hacer N. Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet E. Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet O. Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Topical cyclosporine hydrogel preparation: A new therapeutic option in the treatment of nail psoriasis

Dermatologic Therapy, 2022
Nail psoriasis is a chronic nail disorder that commonly affects psoriatic patients causing severe distress despite the limited body surface area. Treatments for nail psoriasis are limited, as nails are often difficult to treat with topical therapies, and
G. Gallo, L. Mastorino, D. Barilà, F. Cattel, M. Panzone, P. Quaglino, S. Ribero, P. Dapavo   +7 more
semanticscholar   +1 more source

NAPSI utilization as an evaluation method of nail psoriasis in patients using acitretin Utilização do NAPSI como instrumento de avaliação na psoríase ungueal em pacientes com uso da acitretina

Anais Brasileiros de Dermatologia, 2012
BACKGROUND: assessment instruments of nail psoriasis have been published in literature as means to standardize the previous subjective assessments of authors.
Maira Mitsue Mukai, Isabela Fleischfresser Poffo, Betina Werner, Fabiane Mulinari Brenner, José Hermênio Cavalcante Lima Filho   +4 more
doaj   +1 more source

What Is the Future?

, 2014
The major problem when treating nail psoriasis is either the difficulty of the topical medications to present their therapeutic efficacy or the side effects of the systematically administrated drugs.
Antonella Tosti, Dimitris Rigopoulos, Rigopoulos, Dimitris, Tosti, Antonella   +3 more
core   +1 more source

Use of Patient Reported Outcome Measurements Information in Clinical Practice in Spain for the Clinical Management of Psoriasis Patients—Summer Project

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Routine collection of patient perspectives about psoriasis and its treatment through patient reported outcome measurements (PROMs), alongside clinician reported outcome measurements (CROMs), may improve clinical outcomes and facilitate shared decision making.
Jaime Notario, Jorge Magdaleno‐Tapial, Raquel Rivera, Josep Riera‐Monroig, Conrad Pujol, Cynthia Novella, Manuel Cuervas‐Mons, Pablo de la Cueva   +7 more
wiley   +1 more source

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak, Ahmed Javed, Ummi Aiman Rahman, Rumaisa Riaz, Zeeshan Imtiaz, Hassan A. Mirza, Farman U. Khan, Muhid Khattak, Fatima Javid, Abdul Moiz Khan, Adeline L. Roy, Bibek Shrestha   +11 more
wiley   +1 more source

Psoriasis rupioides with marked nail abnormalities in a HIV-positive patient

, 2016
Introduction. Psoriasis rupioides is a rare type of psoriasis. Although a description of it is easy to find in most textbooks of psoriasis, it does not have a place in the ICD-10 classification, and there have been very few case reports published in ...
Iwona Chlebicka, Adam Reich, Jacek Szepietowski   +2 more
core   +1 more source

JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series

JEADV Clinical Practice, EarlyView.
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni, Francois Rosset, Isotta Giunipero di Corteranzo, Lorenzo Bellando, Rebecca Senetta, Simone Ribero, Pietro Quaglino   +6 more
wiley   +1 more source

Nail consistency

, 2005
The changes in brittle, friable nails are often confined to the surface of the nail plate; this occurs in superficial white onychomycosis and may be seen after the application of nail polish or base coat which causes ‘granulations’ in the nail keratin ...

core   +2 more sources

Residual Disease in Adult Psoriasis‐Treated Patients: Frequency, Clinical Aspects, and Management. A Survey Among Dermatologists

JEADV Clinical Practice, EarlyView.
Abstract Background In moderate‐to‐severe psoriasis, residual lesions can be defined as “psoriasis lesions that persist despite well‐managed treatment, and which do not necessarily justify intensification or a change in treatment.” Residual lesions are accepted by guidelines and clinical trials.
Emmanuel Mahé, Nathalie Quiles‐tsimaratos, Bruno Halioua, Antoine Delpuech, Charles Taieb   +4 more
wiley   +1 more source