Results 51 to 60 of about 94,236 (349)

Trajectories of depressive symptoms after hip fracture [PDF]

open access: yes, 2016
BACKGROUND: Hip fracture is often complicated by depressive symptoms in older adults. We sought to characterize trajectories of depressive symptoms arising after hip fracture and examine their relationship with functional outcomes and walking ability. We
Avidan, M. S   +3 more
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

A systematic review and meta‐analysis of randomised controlled trials of surgical treatments for ingrown toenails part II: healing time, post‐operative complications, pain, and participant satisfaction

open access: yesJournal of Foot and Ankle Research, 2023
Background When performing nail surgery, clinicians must choose from a multitude of procedures and variations within each procedure. Much has been published to guide this decision making, but there are a lack of up to date robust systematic reviews to ...
Victoria Exley   +4 more
doaj   +1 more source

Reproducibilty of partial weight bearing [PDF]

open access: yes
Objectives: To find out whether partial weight bearing can be reproduced and retained. Design: In vivo experiment in normal subjects. Intervention: Training for partial weight bearing (25% of body weight) using bathroom scales.
Doyle, J   +4 more
core   +1 more source

Choice of three different intramedullary nails in the treatment of trochanteric fractures: outcome, analysis and consideration in midterm [PDF]

open access: yes, 2019
paragone di 3 differenti impianti per frattura pertrocanterica femoreThe purpose of this study is to compare the results obtained using three different systems of osteosynthesis, developed for the surgical treatment of fractures of the trochanteric ...
De Cristo, Claudia   +7 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Aesthetic satisfaction of patients following plastic surgery of nail folds combined with conservative nail plate reconstruction for ingrown toenails

open access: yesFrontiers in Medicine
IntroductionManagement of ingrown toenails encompasses a wide range of methods, from conservative to surgical approaches, which vary in terms of final aesthetic outcomes and overall patient satisfaction.AimThis study aimed to assess patient aesthetic ...
Tomasz Trochanowski   +4 more
doaj   +1 more source

The first description in the literature, of a complication during the extraction of a retrograde expandable intra-medullary nail in three patients

open access: yesTrauma Case Reports, 2016
Ankle fractures in elderly people are low-energy fractures characterised by fragility. In the majority, they are unstable and challenging to manage.Retrograde expandable intra-medullary nails (Fixion®, Biomet Merck Limited) inserted through the calcaneum
K. Tilkeridis   +4 more
doaj   +1 more source

Clinical practice guidelines for the foot and ankle in rheumatoid arthritis: a critical appraisal [PDF]

open access: yes, 2016
Background: Clinical practice guidelines are recommendations systematically developed to assist clinical decision-making and inform healthcare. In current rheumatoid arthritis (RA) guidelines, management of the foot and ankle is under-represented and the
AE Williams   +53 more
core   +2 more sources

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