Results 121 to 130 of about 48,962 (256)

A Comprehensive Study to Compare Different Compound Representations for Predicting Carcinogenicity In Vivo

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Carcinogenicity evaluation is a critical component of chemical risk assessment, yet traditional in vivo testing remains time consuming, costly, and ethically challenging. Computational approaches based on machine learning offer promising alternatives, but the relative contributions of different molecular representation strategies for ...
Iuri Barbosa Pereira   +2 more
wiley   +1 more source

Early prediction of acute kidney injury in traumatic and non‐traumatic rhabdomyolysis using an interpretable machine learning model: A multicenter study with external validation

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract Acute kidney injury (AKI) is a common and severe complication of rhabdomyolysis (RM), and early risk stratification remains challenging because of its multifactorial and heterogeneous nature. We developed and externally validated an interpretable machine learning (ML) model for early prediction of AKI in RM across traumatic and non‐traumatic ...
Chunli Liu   +11 more
wiley   +1 more source

Explainable, Uncertainty‐Aware Machine Learning for Maize Land Suitability and Climate Resilience in Lorestan Province, Western Iran

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Maize (Zea mays L.) is strategically important in Iran, yet its cultivation in the semi‐arid Zagros is constrained by limited and variable water, heat stress and heterogeneous soils, while conventional suitability assessments are deterministic, rarely validated spatially and provide no measure of confidence.
Ahad Madani, Narges Shafaei Bajestani
wiley   +1 more source

Flow cytometric phytoplankton concentration and optical properties across instruments and laboratories

open access: yesLimnology and Oceanography: Methods, EarlyView.
Abstract Flow cytometry measures the optical properties of individual cells and has become essential for enumerating and characterizing marine phytoplankton. Yet systematic comparison of measurements across instruments remains limited, hampering data comparison across laboratories and long‐term time series.
Francois Ribalet   +10 more
wiley   +1 more source

Sleep‐Autonomic Interactions in Parkinson's Disease and Multiple System Atrophy: A Comparative Study Using Structural Equation Modeling

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) and multiple system atrophy (MSA) are α‐synucleinopathies with overlapping autonomic and sleep dysfunction, but distinct trajectories. Objectives This study compared sleep and autonomic profiles in PD and MSA and elucidated disease‐specific associations using structural equation modeling (SEM).
Bora Jin   +5 more
wiley   +1 more source

Serum elemental profile‐based machine learning models for Alzheimer's disease identification and cognitive score prediction

open access: yesNeuroprotection, EarlyView.
Serum elemental profiling combined with machine learning supports exploratory Alzheimer's disease (AD) identification and cognitive score prediction. In this retrospective cross‐sectional study, 874 participants from the BANC‐PUMC, including cognitively normal controls and patients with AD, were analyzed.
Haotian Liu   +6 more
wiley   +1 more source

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