Results 131 to 140 of about 80,877 (282)
British Journal of Pharmacology, EarlyView.The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan +3 more
wiley +1 more source
Consideration of naloxone. [PDF]
, 2012 The ACMD has been considering the issue of naloxone availability and provision, as an intervention to prevent drug-related deaths, since 2009 and has previously written to the Medicines and Healthcare products Regulatory Agency (MHRA) concerning ...
core
Opioid overdose prevention and naloxone rescue kits: what we know and what we don’t know
Addiction Science & Clinical Practice, 2017 The opioid use and overdose crisis is persistent and dynamic. Opioid overdoses were initially driven in the 1990s and 2000s by the increasing availability and misuse of prescription opioids.
Todd A. Kerensky, A. Walley
semanticscholar +1 more source
Journal of Evidence-Based Medicine, EarlyView.ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li +7 more
wiley +1 more source
Background:Naloxone distributed to people at risk for opioid overdose has been associated with reduced overdose death rates; however, associations of retail pharmacy-distributed naloxone with overdose mortality have not been evaluated.Methods:Our ...
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Supporting Breastfeeding in the Setting of Perinatal Opioid Use Disorder
Journal of Midwifery &Women's Health, EarlyView.Abstract Studies have shown that many pregnant women with opioid use disorder intend to initiate breastfeeding after giving birth. However, continuation rates beyond the initial postpartum hospitalization are low. Achieving and maintaining an antepartum breastfeeding plan may be complicated by the unique challenges that opioid‐exposed dyads experience ...
Lindsey A. Baksh, Stephanie M. Hartwig
wiley +1 more source
Naloxone In Police Scotland: Pilot evaluation [PDF]
, 2022 This report describes the independent findings of an evaluation of a Police Scotland test of change (pilot) of the carriage and administration of naloxone as an emergency first aid measure to persons suspected of experiencing an opioid overdose.
Murray, Jennifer +7 more
core +1 more source
Buprenorphine/naloxone – one formulation that doesn’t fit all: a case report
Harm Reduction JournalBackground Sublingual buprenorphine, approved for treatment of opioid use disorder since 2002, is most commonly available in co-formulation with naloxone.
Hannan M. Braun +2 more
doaj +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont +5 more
wiley +1 more source