Results 131 to 140 of about 65,278 (248)

In Silico, In Vitro, and In Vivo Antinociceptive Potential of S‐Naproxen Derivatives

ChemistryOpen, Volume 15, Issue 4, April 2026.
Selected naproxen derivatives were investigated for their antinociceptive effects, using in vitro (COX‐I/COX‐II antagonistic effect), in vivo (acetic acid and hot plate assay), and in silico (molecular simulation studies) approaches. The COX inhibition studies revealed that the maximum percent effect exhibited by GMO‐I‐111a 96.01 and 92% against COX‐2 ...
Ubaidullah, Naveed Muhammad, Abad Khan, Rahaf Ajaj, Abdur Rauf, Umer Rashid, Fahad Hussain, Rashid Khan, Faiza Seraj, Uzma Uzma, Basharat Ali, Abdul Sadiq, Khalid Mohammed Khan, Marcello Iriti   +13 more
wiley   +1 more source

AAKD: A standardized and comprehensive acupuncture anesthesia knowledge platform for enhanced recovery after surgery and mechanism

VIEW, Volume 7, Issue 2, April 2026.
Acupuncture anesthesia (AA) is an application of acupuncture innovation in surgical operations, combined with anesthetic techniques, and is a model of integrated Chinese and Western medicine. We proposed the Acupuncture Anesthesia Knowledge Database (AAKD), in which all data have been meticulously curated by field experts and assessed by a multi ...
Ying Wang, Honglian Huang, Chenchen Feng, Xueli Zhang, Weiting Wang, Ziyi Wei, Jing Li, Xintong Yu, Hanzhi Lu, Chunfang Gao, Ke Wang, Jia Zhou   +11 more
wiley   +1 more source

Examining the Potential Role of Opioid Settlement Funds in the Face of Impending Federal Budget Reductions for Substance Use Disorders

Health Services Research, Volume 61, Issue 2, April 2026.
ABSTRACT Objective To assess the potential of opioid settlement dollars disbursed to state and local governments to replace or supplement federal substance use disorder (SUD) funding. Study Setting and Design For each state, we calculated the percentage of Substance Use and Mental Health Services Administration (SAMHSA) SUD funding for each state that ...
Zoe Lindenfeld, Amanda I. Mauri, Sachini Bandara, Jonathan H. Cantor, Ryan K. McBain, Abigail Winiker   +5 more
wiley   +1 more source

Scotland's national naloxone program: the prison experience [PDF]

, 2018
Behar, Bird, Bird, Bird, Darke, McAuley, McAuley, Mcgregor, Merrall, Sondhi, Strang, Wright, Zucker   +12 more
core   +1 more source

National opioid pharmacotherapy statistics 2014 [PDF]

Summary Dependence on opioid drugs is associated with a range of health and social problems that affect individual drug users, their family and friends, and the wider public.
Australian Institute of Health and Welfare
core  

Testing of Pre‐Operative Peripheral Nerve Blocks in Randomised Controlled Trials: A Scoping Review

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 4, April 2026.
ABSTRACT Background Peripheral nerve blocks are widely used for anaesthesia in upper and lower limb surgery, but the methods used to assess their success vary substantially. This scoping review examined contemporary research practises and the extent to which trials report on peripheral nerve block evaluation.
Aurelien‐Xuan Rosendal Bahuet, Rasmus Linnebjerg Knudsen, Mathias Therkel Steensbæk, Sina Yousef, Rikke Helene Frølund Bjulf, Anne‐Sofie Linde Jellestad, Jonas Erasmus Egede Glahn, Sine Wichmann, Kai Henrik Wiborg Lange, Lars Hyldborg Lundstrøm, Anders Kehlet Nørskov   +10 more
wiley   +1 more source

Association Between American Society of Anesthesiologists Physical Status Classification System and Remimazolam Sedation Outcomes

Academic Emergency Medicine, Volume 33, Issue 4, April 2026.
ABSTRACT Background Remimazolam (RM) is an ultrashort‐acting benzodiazepine with pharmacodynamic properties ideal for procedural sedation in emergency departments (EDs). This study evaluated the safety of RM when used for procedural sedation of American Society of Anesthesiologists (ASA) I–III patients in the ED. Aims To compare the occurrence of no or
Caroline H. Brynning, Simone P. Busch, Anne L. Krarup, Dorte Melgaard   +3 more
wiley   +1 more source

Contingency management interventions for substance use and addictive behaviours: Review of the United Kingdom evidence base

Addiction, Volume 121, Issue 4, Page 729-746, April 2026.
Abstract Background and aims Substance use and other addictive behaviours including gambling remain major public health concerns in the UK. Despite the effectiveness of substance use treatment approaches, treatment adherence and success rates remain low.
Carol‐Ann Getty, Tricia McQuarrie, Eileen Brobbin   +2 more
wiley   +1 more source

Prison-based prescriptions aid Scotland's National Naloxone Programme [PDF]

, 2017
Bird, Sheila, Hutchinson, Sharon, McAuley, Andrew, Munro, Alison, Taylor, Avril   +4 more
core   +1 more source

Drug use among people in prison: A global review of epidemiology, harms and interventions

Addiction, Volume 121, Issue 4, Page 749-764, April 2026.
Abstract Background and aims People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Louis Favril, John Strang, Seena Fazel
wiley   +1 more source