Results 1 to 10 of about 302,501 (282)

Postoperative Effects of Celecoxib on Opioid Use and Pain Control After Benign Oropharyngeal Surgery

The Laryngoscope, EarlyView.
This study evaluated how the addition of celecoxib to a multimodal pain regimen following tonsillectomy + adenoidectomy, or uvulopalatopharyngoplasty (UPPP) + tonsillectomy affects postoperative opioid use and pain control. Patients who received celecoxib consumed significantly fewer opioids compared to the historic control group, with similar ...
Alana Platukus, Praneet Kaki, Anastasia Kaffenes, Udeerna Tippabhatla, Jared Robinson, Jaehee Kim, Erin Creighton, Meghan Crippen, Maurits Boon, Colin Huntley   +9 more
wiley   +1 more source

Synthetic opioids have disrupted conventional wisdom for treating opioid overdose

Drug and Alcohol Dependence Reports
More than 90 % of opioid overdose deaths in North America are now caused by synthetic opioids, and while they are not as prevalent in the European illicit drug market, there are indications that they may become so in the near future.
Phil Skolnick, Jordan Paavola, Christian Heidbreder   +2 more
doaj   +1 more source

Nanoelectronic Detection of Opioids: Machine Learning‐Powered Screening With Carbon Nanotube Field‐Effect Transistor Sensor Array

Small, EarlyView.
A carbon nanotube field‐effect transistor (NTFET) sensor array is constructed to screen different opioids with machine learning models. Codeine, fentanyl, hydrocodone, and morphine are tested using the NTFET sensor array and classified with both conventional supervised learning models and deep learning models.
Zhengru Liu, Mehdy Dousty, Wenting Shao, Jieyu Wang, Samia Afrin, Wuqi Li, Ervin Sejdić, Alexander Star   +7 more
wiley   +1 more source

The Dark Pyramid: Unpacking the Multidimensional Nature of the Dark Side of Leadership

British Journal of Management, EarlyView.
Abstract The dark side of leadership has been employed as an umbrella term to cover an array of concepts typically concerned with the dysfunctionality and/or toxicity of individual leaders. As the field of leadership studies moves towards ‘post‐heroic’ perspectives, we apply the same ontological positioning, adopting a ‘post‐villainous’ perspective in ...
Peter Stephenson, Richard Bolden, Morgen Witzel   +2 more
wiley   +1 more source

Psychiatry and the Opioid Overdose Crisis

Focus, 2019
For the third year in a row, the Centers for Disease Control and Prevention reported an unprecedented decline in life expectancy for the United States, a decline attributable mainly to drug overdose deaths and suicides. Drug overdoses have continued to rise and are now estimated to account for 70,237 deaths in 2017. The root causes of the modern opioid
Bertha K, Madras, Hilary, Connery
openaire   +3 more sources

Firearms as a Market‐Driven Epidemic: Potential Pathways to Reduce Preventable Firearm‐Related Harm in the United States

The Milbank Quarterly, EarlyView.
Policy Points For half a century, firearm‐related deaths and injuries have been endemic in the United States, with COVID‐19 contributing to a record high of 48,830 deaths in 2021, an epidemic rate increase. By 2023, national trends masked a significant 10‐fold difference in firearm‐related death rates among states.
ESZTER RIMÁNYI, JONATHAN D. QUICK, STEPHEN W. HARGARTEN, CHARLES C. BRANAS, SANDRO GALEA, NASON MAANI, JONATHAN LOWY, ZAIN HUSSAIN, NICHOLAS HOFFMANN   +8 more
wiley   +1 more source

Impacts of Global Cannabis Policy Changes on Substance Use: A Systematic Review of Quasi‐Experimental Studies

The Milbank Quarterly, EarlyView.
Policy Points The liberalization of medical and recreational cannabis policies may increase cannabis initiation across age groups, with increased prevalence of cannabis use among young adults and adults and weaker effects among youth. Evidence also suggests increases in cannabis‐related health care utilization among adults.
SARAH B. WINDLE, PETER M. SOCHA, JASLEEN ARNEJA, SAM HARPER, GENEVIEVE GORE, GENEVIÉVE GARIÉPY, EVA GRAHAM, ANDREA BENEDETTI, ARIJIT NANDI   +8 more
wiley   +1 more source

Collateral Damage: Neurological Correlates of Non-Fatal Overdose in the Era of Fentanyl-Xylazine

Neuroscience Insights
Non-fatal opioid overdoses are associated with significant morbidity. Hypoxic brain injury caused by opioid-induced respiratory depression is a key mechanism of such morbidity. For example, reports describe an amnestic syndrome in opioid users associated
Dustin R Todaro, Nora D Volkow, Daniel D Langleben, Zhenhao Shi, Corinde E Wiers   +4 more
doaj   +1 more source

Investigation of eosin Y as a colorimetric sensor for the detection of fentanyl hydrochloride and fentanyl freebase

Journal of Forensic Sciences, EarlyView.
Abstract The increasing prevalence of fentanyl within the illegal global drug market underscores the need for rapid, low‐cost, and straightforward detection methods. Eosin Y demonstrates a measurable color change in the presence of fentanyl, making it a promising candidate for colorimetric sensing and preliminary identification of fentanyl ...
Alan J. Zhou, Melissa M. Dixon, Brady S. Gentle, Genevieve H. Dennison, Kellie L. Tuck   +4 more
wiley   +1 more source

A Case of Opioid Overdose? Or Is It? [PDF]

The Journal of Applied Laboratory Medicine, 2018
A 28-year-old man was found unresponsive at home by a roommate. When emergency medical services (EMS) arrived, he was found to have miosis and was cyanotic with respiratory depression. He was unresponsive to intranasal naloxone (2 mg) that was administered via mucosal atomizer twice.
Deborah, French, Roy R, Gerona
openaire   +2 more sources