Results 41 to 50 of about 156,077 (286)

Preventing opioid overdose with peer-administered naloxone: findings from a rural state

Harm Reduction Journal, 2020
Background In response to the opioid epidemic, naloxone distribution programs aim to prevent overdose death by making naloxone available and training people to use it.
Bridget L. Hanson, Rebecca R. Porter, Amanda L. Zöld, Heather Terhorst-Miller   +3 more
doaj   +1 more source

Impact of COVID-19 Pandemic, Social Vulnerability, and Opioid Overdoses in Chicago

AJPM Focus, 2023
Introduction: This research was undertaken to examine the individual and neighborhood drivers that contributed to increases in opioid overdose deaths during the COVID-19 pandemic.
Randall W. Knoebel, PharmD, MPH, Sage J. Kim, PhD   +1 more
doaj   +1 more source

Association of Household Opioid Availability With Opioid Overdose

JAMA Network Open, 2023
ImportancePrevious studies that examined the role of household opioid prescriptions in opioid overdose risk were limited to commercial claims, did not include fatal overdoses, and had limited inclusion of household prescription characteristics. Broader research is needed to expand understanding of the risk of overdose.ObjectiveTo assess the role of ...
Hendricks, Michelle A., El Ibrahimi, Sanae, Ritter, Grant A., Flores, Diana, Fischer, Michael A., Weiss, Roger D., Wright, Dagan A., Weiner, Scott G.   +7 more
openaire   +2 more sources

No obvious effect on mortality from a patient choice reform expanding access to opioid disorder treatment – results from a natural experiment of policy change in Sweden

Substance Abuse Treatment, Prevention, and Policy, 2023
Background Opioid-related overdose deaths remain a common cause of death in many settings, and opioid maintenance treatment is evidence-based for the treatment of opioid use disorders.
Anders Håkansson, Sahar Janfada-Baloo, Jonas Berge   +2 more
doaj   +1 more source

Opioid Dosage Levels, Concurrent Risk Factors and Self-Perceptions among Chronic Pain, Opioid-Managed Individuals at Elevated Risk for Opioid Overdose

Pharmaceuticals, 2021
While current opioid prescribing guidelines highlight a dose-response relationship between therapeutic management and overdose risk, other concurrent risk factors have also been identified.
Matthew S. Ellis, Zachary A. Kasper, Mark Gold, Theodore J. Cicero   +3 more
doaj   +1 more source

Factors associated with opioid overdose during medication-assisted treatment: How can we identify individuals at risk?

Harm Reduction Journal, 2021
Background Due to the loss of tolerance to opioids during medication-assisted treatment (MAT), this period may represent a time of heightened risk for overdose.
Vivian Y. O. Au, Tea Rosic, Nitika Sanger, Alannah Hillmer, Caroul Chawar, Andrew Worster, David C. Marsh, Lehana Thabane, Zainab Samaan   +8 more
doaj   +1 more source

Impact of UNODC/WHO S-O-S (stop-overdose-safely) training on opioid overdose knowledge and attitudes among people at high or low risk of opioid overdose in Kazakhstan, Kyrgyzstan, Tajikistan and Ukraine

Harm Reduction Journal
Introduction Opioid overdose education and naloxone distribution (OEND) is an evidence-based strategy to reduce opioid overdose deaths in line with guidance provided by the World Health Organization (WHO) and United Nations Office on Drugs and Crime ...
Paul Dietze, Samantha Colledge-Frisby, Gilberto Gerra, Vladimir Poznyak, Giovanna Campello, Wataru Kashino, Dzhonbek Dzhonbekov, Tetiana Kiriazova, Danil Nikitin, Assel Terlikbayeva, Kirsten Horsburgh, Anja Busse, Dzmitry Krupchanka   +12 more
doaj   +1 more source

Opioid-related overdose and chronic use following an initial prescription of hydrocodone versus oxycodone.

PLoS ONE, 2022
BackgroundHydrocodone and oxycodone are prescribed commonly to treat pain. However, differences in risk of opioid-related adverse outcomes after an initial prescription are unknown.
Scott G Weiner, Michelle A Hendricks, Sanae El Ibrahimi, Grant A Ritter, Sara E Hallvik, Christi Hildebran, Roger D Weiss, Edward W Boyer, Diana P Flores, Lewis S Nelson, Peter W Kreiner, Michael A Fischer   +11 more
doaj   +1 more source

Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]

, 2015
Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Pilgrim, Jennifer, Hall, WD ; https://orcid.org/, Amanda Roxburgh, Saar, E, Nielsen, Suzanne, Hall, Wayne D., Degenhardt, L ; https://orcid.org/, Jennifer Pilgrim, Louisa Degenhardt, Eva Saar, Pilgrim, J, Lucinda Burns, Degenhardt, Louisa, Nielsen, S ; https://orcid.org/, Roxburgh, A ; https://orcid.org/, Suzanne Nielsen, Burns, L ; https://orcid.org/, Wayne D Hall, Roxburgh, Amanda, Burns, Lucinda, Saar, Eva   +20 more
core   +1 more source

Adipose‐derived mesenchymal stem cell injection into the KI10 acupoint mitigates cartilage damage in KOA rats through PGE2‐mediated α7nAChR/NF‐κB pathway

Animal Models and Experimental Medicine, EarlyView.
In our research, KOA rat models were established and treated with ADSC injection into the KI10 acupoint. Pain relief, behavioral function, and joint structural improvements were systematically assessed using ethological tests, imaging, histopathological staining, transmission electron microscopy, and molecular analyses.
Mengwei Dong, Wenfang Li, Wanpeng Yang, Te Ba, Nan Nan, Yang Liu, Jing Han, Huiqin Hao   +7 more
wiley   +1 more source