Results 151 to 160 of about 25,222 (249)

Extended‐release buprenorphine in adults with opioid use disorder involving poppy seed tea: An 18‐month retrospective case series

The American Journal on Addictions, Volume 35, Issue 5, Page 638-642, September 2026.
Abstract Background and Objectives Poppy seed tea (PST) contains unpredictable opioid concentrations, destabilising tolerance and increasing overdose risk. Extended‐release buprenorphine (BUP‐XR) provides sustained coverage without daily dosing. Methods Eighteen‐month follow‐up of adults (N = 3) with opioid use disorder (OUD) involving PST in Australia.
John McMaster, Saumiya Seshakumaran, Hesitha Abeysundera, Isha Tipirneni, Rita Hormiz   +4 more
wiley   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, Volume 183, Issue 18, Page 5458-5475, September 2026.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, Volume 105, Issue 3, Page 271-284, September 2026.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Contemporary Approaches to Opioid Dependence Treatment Delivery: A Rapid Review of Novel Models Relevant to Implementation in Victoria, Australia

Drug and Alcohol Review, Volume 45, Issue 6, September 2026.
ABSTRACT Issues Rising opioid‐related harms and persistent barriers to opioid dependence treatment (ODT) access present critical challenges across Australia and internationally. Pharmacotherapy remains the most effective treatment for opioid use disorder, yet systemic gaps in workforce availability and service models limit reach and sustainability ...
Shalini Arunogiri, Ali Cheetham, Michael Savic, Dan I. Lubman, Victoria Manning   +4 more
wiley   +1 more source

Effectiveness of Alcohol Use Disorder Pharmacotherapies by Sex: Systematic Review and Meta-Analysis. [PDF]

Drug Alcohol Rev
Allen J, Jones A, Shorter GW, Montgomery C, Kougiali Z, Bagnall A, Adshead C, Smith J, Burton S, Atkinson A, Guelen L, Rose A.   +11 more
europepmc   +1 more source

Opioid antagonist treatment in alcohol use disorder: extinction, reward memory, and the possible importance of timing. [PDF]

Front Neurosci
Jääskeläinen IP.
europepmc   +1 more source

Tirzepatide Efficacy and Tolerability According to Early Weight Response: A Post Hoc Analysis of the SURMOUNT‐1 and SURMOUNT‐2 Trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8367-8377, September 2026.
ABSTRACT Aims Obesity affects over 800 million people globally and is associated with complications including cardiovascular disease and type 2 diabetes (T2D). Early response to weight loss interventions may help optimize achievement of individual treatment goals.
Alexander Kokkinos, Tina Thethi, Clare J. Lee, Lisa M. Neff, Adam Stefanski, Dachuang Cao, Angel Rodriguez, Amy Bartee   +7 more
wiley   +1 more source

Naltrexone for Acute Management of Compulsive Sexual and Obsessive Symptoms in a Patient With a Neurodevelopmental Disorder. [PDF]

Case Rep Psychiatry
Constantin E, Deol MS, Yaun J, Singh H, Glass OM.   +4 more
europepmc   +1 more source

Positioning Incretin‐Based and Next‐Generation Obesity Management Medications: A Methodological Framework for a Series of Systematic Reviews and Network Meta‐Analyses

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 7768-7778, September 2026.
ABSTRACT Background The obesity pharmacotherapy landscape is evolving rapidly, with several approved incretin‐based therapies and an expanding pipeline of investigational compounds targeting multiple metabolic pathways. Conventional evidence syntheses often struggle to accommodate differences in dose selection, treatment duration and stage of clinical ...
Matteo Monami, Benedetta Ragghianti, Edoardo Mannucci   +2 more
wiley   +1 more source

Effect of low-dose naltrexone for long COVID: a systematic review and meta-analysis. [PDF]

BMJ Open
Byambasuren O, Atkins T, Baptista S, Glasziou P, Chakraborty S.   +4 more
europepmc   +1 more source