Results 81 to 90 of about 25,222 (249)

Predicting individual treatment response in alcohol use disorders: a reverse translational proof-of-concept study

Translational Psychiatry
The development of medications for alcohol use disorders (AUD) faces stagnation, as promising drugs failed to translate in clinic. Screening on homogeneous groups of animals drugs later tested on heterogeneous clinical cohorts may contribute to the ...
Sara De Carlo, Hela Mrizak, Andrea Della Valle, Veronica Lunerti, Manthoula O. Kyratzi, Alessandra Mammone, Antonio Lacorte, Adana Keshishian, Min Li, Esi Domi, Di Qin, Leah Solberg Woods, Laura Soverchia, Massimo Ubaldi, Roberto Ciccocioppo, Nazzareno Cannella   +15 more
doaj   +1 more source

Achieving long-term continuous blood naltrexone and 6-β-naltrexol coverage following sequential naltrexone implants

, 2004
The aim of this study was to assess blood free naltrexone and 6-β-naltrexol levels with time following treatment with sequential sustained-release naltrexone preparations. Data were collected from blood samples analysed independently for naltrexone and 6-
Hansson, Robert C, Hulse, Gary K, Chan, C-T, Arnold-Reed, Diane, O\u27Neil, George, O\u27Neil, P   +5 more
core   +1 more source

How common is alcohol use disorder in posttraumatic stress disorder? A systematic review, meta‐analysis, and moderator analysis

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Comorbidity between posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) complicates care, yet reported prevalence varies widely across settings and methods. We estimated AUD prevalence among adults with PTSD and identified sources of variability.
Maria Olivia Pozzolo Pedro, Manoela Pozzolo Pedro, Gabriella Zimmer Monteiro, Valquíria Custodio Klaumann, Priscila Dib Gonçalves, Silvia S. Martins, João Maurício Castaldelli‐Maia   +6 more
wiley   +1 more source

Does Prolonged Naltrexone Therapy Alter the Rewarding Nature of Exercise, Socialization, and Eating? A Narrative Review

McGill Journal of Medicine
Introduction: Naltrexone is an opioid receptor antagonist prescribed for alcohol use disorder and opioid use disorder.  Naltrexone has a high affinity for the mu-opioid receptors, which are the primary binding site of beta-endorphin.
Caitlin Collier, Thomas Hilton
doaj   +1 more source

Letter to the editor: naltrexone sustained-release/bupropion sustained-release for the management of obesity: review of the data to date

, 2015
Anna M Buehler Hospital Alemao Oswaldo Cruz, Institute of Health Education and Sciences, Sao Paulo, BrazilI read with great interest the systematic review by Caixàs et al1 on the effect of naltrexone sustained-release/bupropion sustained-release (
Buehler AM
core  

Opioid withdrawal syndrome‐associated cognitive impairment: A narrative review

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Opioid withdrawal syndrome (OWS) comprises a transient constellation of subjective symptoms and objective signs expressed by brain and other organs. Although cognitive impairment is well documented in opioid use and addiction, little is known about cognitive impairment that may specifically accompany OWS.
Faizan Khan, Nazli Tunali, R. Andrew Chambers   +2 more
wiley   +1 more source

Extemporaneous Preparation and Effectiveness of Low-Dose Naltrexone for the Treatment of Uremic Pruritus: A Literature Review and Case Report

Pharmacy
Background: Uremic pruritus is one of the most debilitating complications among patients with end-stage kidney disease (ESKD) receiving hemodialysis.
Dhakrit Rungkitwattanakul, Michelle Brooks, Simeon Adesina, Sanaa Belrhiti, Weerachai Chaijamorn, Taniya Charoensareerat, Uzoamaka Nwaogwugwu, Constance Mere   +7 more
doaj   +1 more source

Dyskinesias occur in response to saline and naltrexone alone after priming with combination of dopaminergic agents and naltrexone in the MPTP parkinsonian monkeys

Neurobiology of Disease, 2005
Storage of motor memory involves the basal ganglia and more precisely the striatum, which receives afferents from all regions of the cerebral cortex.
Pershia Samadi, Laurent Grégoire, Claude Rouillard, Paul J. Bédard   +3 more
doaj   +1 more source

Pruritus Is Frequent and Persistent and Impacts Quality of Life Among Patients With Primary Sclerosing Cholangitis

Alimentary Pharmacology &Therapeutics, EarlyView.
Among 200 patients with primary sclerosing cholangitis, 38% reported moderate to severe pruritus in the past 6 months. During 6 months of follow up, pruritus severity fluctuated significantly. Pruritus severity was linked to worse colitis activity and lower quality of life.
Richard Dean, Maryam Yazdanfar, Joseph Zepeda, Isha J. Patel, Cynthia Levy, Craig Lammert, Raghav Bordia, Duru Cosar, Katherine Specht, Daniel Pratt, Stuart C. Gordon, Lisa Forman, Fawzy Barry, Michael Li, Usha Gungabissoon, Megan M. McLaughlin, Christopher L. Bowlus   +16 more
wiley   +1 more source

Evaluation of a prison-based naltrexone program

, 2007
The study evaluated the introduction of naltrexone in an Australian prison system for imprisoned male heroin users. Treatment outcomes were analysed for two sub‐samples taken from an unsuccessful randomised controlled trial. The first sample comprised 68
Dolan, Kate A., Shearer, James; id_orcid, Wodak, Alex D.   +2 more
core   +1 more source