Results 71 to 80 of about 22,433 (204)

National and International Clinical Guidelines for the Management of Obesity in Adults: A Systematic Review

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is a leading risk factor for premature morbidity and mortality, and an increasing public health challenge. This review aimed to systematically identify and appraise national and international clinical guidelines for the management of obesity in adults.
Paul Doody   +7 more
wiley   +1 more source

Pharmacological enhancement of naltrexone treatment for opioid dependence: a review.

open access: yes, 2011
PURPOSE: Opioid dependence (OD) is a serious and growing clinical condition with increasing social costs that requires expanding treatment beyond opioid agonist substitution.
Wu, Li-Tzy   +2 more
core   +1 more source

Effectiveness of a Psychiatrist‐Led Clinic for Metabolic Health in Severe Mental Illness: A Retrospective Chart Review Study

open access: yesActa Psychiatrica Scandinavica, Volume 154, Issue 1, Page 74-88, July 2026.
ABSTRACT Background Psychotropic medications are associated with serious metabolic adverse effects, which contribute to an increased risk of cardiometabolic comorbidities in patients with severe mental illness (SMI). Several intervention strategies are available to mitigate these metabolic adverse effects; however, data on their utility in real‐world ...
Nicolette Stogios   +17 more
wiley   +1 more source

PhD

open access: yes, 2007
dissertationDevelopment of a polymeric naltrexone delivery system would give an effective means for treatment of opiate addiction. A novel approach involves synthesis and characterization of a biodegradable polymeric prodrug of naltrexone covalently ...
Bennett, David Bruce
core  

Experiences of a Pre‐Treatment Sober Month in Individuals With Alcohol Use Disorder Pursuing Controlled Drinking Goals

open access: yesDrug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Interest in managing alcohol‐related risks through temporary abstinence challenges has grown significantly. Studies on abstinence challenges in the general population show improvements in for example mental health, blood pressure, insulin resistance and alcohol consumption, but studies in clinical samples are lacking, including ...
Stina Ingesson‐Hammarberg   +5 more
wiley   +1 more source

Serum levels of naltrexone and 6-beta-naltrexol after oral naltrexone in patients with liver cirrhosis

open access: yes, 1993
liver cirrhosis induces important changes in the time-course of naltrexone with higher bioavailability of naltrexone and slower conversion to 6-beta ...
FERRARI, Anna   +6 more
core  

Prevalence and Correlates of Reporting a Gabapentin Prescription for Pain Among People Who Use Opioids: A Longitudinal Community‐Recruited Study

open access: yesDrug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Gabapentin is widely prescribed off‐label to treat pain. However, there are concerns about the proliferation of medical and non‐medical use, and the potential increased risk of overdose death associated with concurrent opioid use.
Evelyne Marie Piret   +7 more
wiley   +1 more source

Semaglutide 2.4 mg Cardiometabolic Long‐Term Effects in Patients With Obesity or Overweight in a Real‐World Setting: A Retrospective Cohort Study in the United States (SMILE)

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 6121-6130, July 2026.
ABSTRACT Aims To evaluate the real‐world associations between semaglutide 2.4 mg and cardiometabolic comorbidities, biomarkers and cardiovascular risk among adults with overweight or obesity. Methods This retrospective cohort study used US claims data and laboratory measurements from the Komodo Research Database (2016–2024). Adults with obesity or with
Aleksandrina Ruseva   +11 more
wiley   +1 more source

Associations of Semaglutide With Skeletal Outcomes in People With Obesity, With and Without Type 2 Diabetes: A Target Trial Emulation

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5834-5847, July 2026.
ABSTRACT Aims To evaluate the associations between semaglutide initiation and long‐term skeletal outcomes in people with obesity, stratified by type 2 diabetes (T2D) status, using target trial emulation. Materials and Methods This retrospective cohort study used the TriNetX federated electronic health record network.
Yu‐Nan Huang   +8 more
wiley   +1 more source

Il naltrexone nel trattamento del prurito

open access: yes, 2005
Naltrexone is a cyclopropyl derivative of oxymorphone which behaves as a competitive antagonist of opioid receptors. Naltrexone is usually used in weaning opioid-dependent patients.
S. Veraldi, R. Caputo
core  

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