Results 71 to 80 of about 22,433 (204)
ABSTRACT Obesity is a leading risk factor for premature morbidity and mortality, and an increasing public health challenge. This review aimed to systematically identify and appraise national and international clinical guidelines for the management of obesity in adults.
Paul Doody +7 more
wiley +1 more source
Pharmacological enhancement of naltrexone treatment for opioid dependence: a review.
PURPOSE: Opioid dependence (OD) is a serious and growing clinical condition with increasing social costs that requires expanding treatment beyond opioid agonist substitution.
Wu, Li-Tzy +2 more
core +1 more source
ABSTRACT Background Psychotropic medications are associated with serious metabolic adverse effects, which contribute to an increased risk of cardiometabolic comorbidities in patients with severe mental illness (SMI). Several intervention strategies are available to mitigate these metabolic adverse effects; however, data on their utility in real‐world ...
Nicolette Stogios +17 more
wiley +1 more source
dissertationDevelopment of a polymeric naltrexone delivery system would give an effective means for treatment of opiate addiction. A novel approach involves synthesis and characterization of a biodegradable polymeric prodrug of naltrexone covalently ...
Bennett, David Bruce
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ABSTRACT Introduction Interest in managing alcohol‐related risks through temporary abstinence challenges has grown significantly. Studies on abstinence challenges in the general population show improvements in for example mental health, blood pressure, insulin resistance and alcohol consumption, but studies in clinical samples are lacking, including ...
Stina Ingesson‐Hammarberg +5 more
wiley +1 more source
liver cirrhosis induces important changes in the time-course of naltrexone with higher bioavailability of naltrexone and slower conversion to 6-beta ...
FERRARI, Anna +6 more
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ABSTRACT Introduction Gabapentin is widely prescribed off‐label to treat pain. However, there are concerns about the proliferation of medical and non‐medical use, and the potential increased risk of overdose death associated with concurrent opioid use.
Evelyne Marie Piret +7 more
wiley +1 more source
ABSTRACT Aims To evaluate the real‐world associations between semaglutide 2.4 mg and cardiometabolic comorbidities, biomarkers and cardiovascular risk among adults with overweight or obesity. Methods This retrospective cohort study used US claims data and laboratory measurements from the Komodo Research Database (2016–2024). Adults with obesity or with
Aleksandrina Ruseva +11 more
wiley +1 more source
ABSTRACT Aims To evaluate the associations between semaglutide initiation and long‐term skeletal outcomes in people with obesity, stratified by type 2 diabetes (T2D) status, using target trial emulation. Materials and Methods This retrospective cohort study used the TriNetX federated electronic health record network.
Yu‐Nan Huang +8 more
wiley +1 more source
Il naltrexone nel trattamento del prurito
Naltrexone is a cyclopropyl derivative of oxymorphone which behaves as a competitive antagonist of opioid receptors. Naltrexone is usually used in weaning opioid-dependent patients.
S. Veraldi, R. Caputo
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