Results 51 to 60 of about 18,364 (184)
BackgroundNaltrexone is an opioid receptor antagonist. Naltrexone is used to block the euphoric and sedative effects of drugs such as heroin, codeine, and morphine.
Nor Asiah Muhamad +10 more
doaj +1 more source
Heat stroke is characterized by hyperthermia, arterial hypotension, decreased baroreflex sensitivity, and increased serum levels of β-endorphin. Whereas naltrexone may have therapeutic potential in heat stroke, the underlying mechanism remains unclear ...
Yi-Ping Huang +3 more
doaj +1 more source
Comparison of Disulfiram and Naltrexone in Cases of Alcohol Dependence Syndrome
Background: Relapse prevention in alcoholism is recognised as an important component of management. Use of pharmacotherapies to prevent relapse in combination to psychological intervention is emerging.
Sandarba Adhikari +5 more
doaj +1 more source
The association between sleep disturbance and stimulant use: A cross‐lagged examination
Abstract Background and aims Sleep disruptions increase the risk of substance misuse. Substance use—especially stimulants—can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).
Viviana E. Horigian +12 more
wiley +1 more source
Abstract Background and Objectives Readmission to residential treatment increases healthcare costs, strains publicly funded systems, and may not adequately meet clients' needs. This study examined rates and predictors of readmission to residential treatment among clients transitioned from detoxification services.
Abreham Mekonnen
wiley +1 more source
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo +13 more
wiley +1 more source
Background Hailey–Hailey disease (HHD), a genetic blistering disease, is caused by a mutation in a calcium transporter protein in the Golgi apparatus encoded by the ATP2C1 gene.
Junyou Zheng +7 more
doaj +1 more source
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source

