Results 41 to 50 of about 22,449 (147)

Naltrexone Reverses Ethanol Preference and Protein Kinase C Activation in Drosophila melanogaster [PDF]

open access: yes
Alcohol use disorder (AUD) is a major health, social and economic problem forwhich there are few effective treatments. The opiate antagonist naltrexone is currently prescribed clinically with mixed success.
Ayoub, Samir   +5 more
core   +1 more source

Pharmacological enhancement of naltrexone treatment for opioid dependence: a review. [PDF]

open access: yes, 2011
PURPOSE: Opioid dependence (OD) is a serious and growing clinical condition with increasing social costs that requires expanding treatment beyond opioid agonist substitution.
Wu, Li-Tzy   +2 more
core   +1 more source

PhD [PDF]

open access: yes, 2007
dissertationDevelopment of a polymeric naltrexone delivery system would give an effective means for treatment of opiate addiction. A novel approach involves synthesis and characterization of a biodegradable polymeric prodrug of naltrexone covalently ...
Bennett, David Bruce
core  

Serum levels of naltrexone and 6-beta-naltrexol after oral naltrexone in patients with liver cirrhosis [PDF]

open access: yes, 1993
liver cirrhosis induces important changes in the time-course of naltrexone with higher bioavailability of naltrexone and slower conversion to 6-beta ...
FERRARI, Anna   +6 more
core  

Il naltrexone nel trattamento del prurito [PDF]

open access: yes, 2005
Naltrexone is a cyclopropyl derivative of oxymorphone which behaves as a competitive antagonist of opioid receptors. Naltrexone is usually used in weaning opioid-dependent patients.
S. Veraldi, R. Caputo
core  

Oral naltrexone maintenance treatment for opioid dependence. [PDF]

open access: yes, 2011
Opioid dependence is considered to be a lifelong, chronic relapsing disorder. Substantial therapeutic efforts are needed to keep people drug free. Methadone treatment plays a vital role in detoxification or maintenance programs but some individuals who ...
Silvia Minozzi   +11 more
core   +1 more source

Memantine enhances the inhibitory effects of naltrexone on ethanol consumption [PDF]

open access: yes, 2008
Effects of the opioid receptor antagonist naltrexone (0.1; 0.3; 1.0 mg/kg i.p.) on operant ethanol self-administration alone and in combination with the non-competitive NMDA antagonist memantine (0.5 and 1 mg/kg, i.p.) were studied in rats.
Kuzmin, A, Stenback, T, Liljequist, S
core   +1 more source

Plasma time-course of naltrexone and 6beta-naltrexol after oral naltrexone administration in patients with liver cirrhosis [PDF]

open access: yes, 1993
BACKGROUND/AIMS: Naltrexone has been proposed as a possible treatment of pruritus in cholestasis.These studies were undertaken to evaluate the effect of liver cirrhosis on the plasma time-course of naltrexone.
FERRARI, Anna   +5 more
core  

Treatment with naltrexone [PDF]

open access: yes, 1995
The procedures of naltrexone treatment for the maintenance of a drug-free state from opioids are described. Treatment with naltrexone (a competitive antagonist of the opioid receptors with oral activity and long duration of action) must be employed in ...
E. Sternieri, FERRARI, Anna
core  

Evaluation of Naltrexone as a treatment for amphetamine dependence [PDF]

open access: yes, 2007
Amphetamine addiction is a disease that affects millions of people worldwide and lacks effective treatment. An estimated 35 million persons are reported to abuse amphetamines, which is more than the total number of cocaine and heroin abusers combined.
Nitya Jayaram-Lindström (317917)
core  

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