Results 21 to 30 of about 18,364 (184)

Naltrexone Inhibits IL-6 and TNFα Production in Human Immune Cell Subsets following Stimulation with Ligands for Intracellular Toll-Like Receptors

Frontiers in Immunology, 2017
The opioid antagonist naltrexone hydrochloride has been suggested to be a potential therapy at low dosage for multiple inflammatory conditions and cancers.
Rachel Cant, Angus G. Dalgleish, Rachel L. Allen   +2 more
doaj   +1 more source

Naltrexone

, 2006
europepmc   +2 more sources

Naltrexone therapeutic drug monitoring: A case series

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Naltrexone is an opioid receptor antagonist.It is used in maintanence treatment of opiate dependence,alcohol dependence, prevention of relapse of alcohol dependence, treatment of cocaine dependence, nicotine dependence, eating disorders ...
Birim Sungu Danışmant, Nesrin Dilbaz, Esra Sağlam, Kaşif Nevzat Tarhan   +3 more
doaj  

Naltrexone Treatment for Methamphetamine Dependence – Service Evaluation Audit

BJPsych Open
Aims There is an emerging evidence base to support the benefit of naltrexone prescription in methamphetamine dependence. This audit assesses prescribing practice and benefit of naltrexone in a specialist NHS drug service based in West London.
Emma Stimson, Owen Bowden-Jones
doaj   +1 more source

Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study

Frontiers in Pharmacology, 2020
Opioids are broad spectrum analgesics that are an integral part of the therapeutic armamentarium to combat pain in the clinical practice. Unfortunately, together with analgesia, a number of adverse effects can occur such as nausea, vomiting, constipation,
Laura Micheli, Lorenzo Di Cesare Mannelli, Elena Lucarini, Carmen Parisio, Alessandra Toti, Bruno Fiorentino, Maria Adele Rigamonti, Laura Calosi, Carla Ghelardini   +8 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Design and Construction of a Naltrexone Selective Sensor Based on Computational Study for Application in Pharmaceutical Analysis

International Journal of Electrochemical Science, 2009
Naltrexone is an opioid antagonist, which has been used for treatment of alcoholism and opiate dependence. In this study, the electronic and geometric properties of Naltrexone, sodium tetraphenyl borate and their complexes were studied by computational ...
Mohammad Reza Ganjali, Aidin Alipour, Siavash Riahi, Parviz Norouzi   +3 more
doaj   +1 more source

Quantitative Determination of Naltrexone Hydrochloride in a Nasal Spray by High-performance Liquid Chromatography

Разработка и регистрация лекарственных средств, 2020
Introduction. Naltrexone, an antagonist of µ-opioid receptors, is promising for the treatment of various autoimmune and oncological diseases when used in doses of 1.5–5 mg/day. To date, there are no medications that provide such dosages of naltrexone.Aim.
Yu. M. Domnina, V. V. Suslov, S. A. Kedik, E. V. Vorfolomeeva, A. V. Meleshko   +4 more
doaj   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Naltrexone Reverses Ethanol Preference and Protein Kinase C Activation in Drosophila melanogaster

Frontiers in Physiology, 2018
Alcohol use disorder (AUD) is a major health, social and economic problem for which there are few effective treatments. The opiate antagonist naltrexone is currently prescribed clinically with mixed success.
Rajeswari Koyyada, Nilesh Latchooman, Julius Jonaitis, Samir S. Ayoub, Olivia Corcoran, Stefano O. Casalotti   +5 more
doaj   +1 more source