Results 31 to 40 of about 25,222 (249)
Addiction Neuroscience, 2023 The non-selective opioid receptor antagonist, naltrexone is one of the most prescribed medications for treating alcohol and opioid addiction. Despite decades of clinical use, the mechanism(s) by which naltrexone reduces addictive behavior remains unclear.
Cory N. Spencer +5 more
doaj +1 more source
Annals of Neurology, EarlyView.Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl +10 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad +4 more
wiley +1 more source
Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study
Frontiers in Pharmacology, 2020 Opioids are broad spectrum analgesics that are an integral part of the therapeutic armamentarium to combat pain in the clinical practice. Unfortunately, together with analgesia, a number of adverse effects can occur such as nausea, vomiting, constipation,
Laura Micheli +8 more
doaj +1 more source
, 2009 The purpose of this study was to evaluate the comparative cost of treating alcohol dependence with either cognitive behavioral therapy (CBT) alone or CBT combined with naltrexone (CBT+naltrexone). Two hundred ninety-eight outpatients dependent on alcohol
Connor, Jason P. +10 more
core +1 more source
Economic evaluations of antiobesity medications: A systematic literature review
British Journal of Clinical Pharmacology, EarlyView.The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković +5 more
wiley +1 more source
Разработка и регистрация лекарственных средств, 2020 Introduction. Naltrexone, an antagonist of µ-opioid receptors, is promising for the treatment of various autoimmune and oncological diseases when used in doses of 1.5–5 mg/day. To date, there are no medications that provide such dosages of naltrexone.Aim.
Yu. M. Domnina +4 more
doaj +1 more source
International Journal of Electrochemical Science, 2009 Naltrexone is an opioid antagonist, which has been used for treatment of alcoholism and opiate dependence. In this study, the electronic and geometric properties of Naltrexone, sodium tetraphenyl borate and their complexes were studied by computational ...
Mohammad Reza Ganjali +3 more
doaj +1 more source
Naltrexone implant and blood naltrexone levels over pregnancy
, 2003 Approximately 80–90% of all women using intravenous heroin are of reproductive age. Although heroin use can cause menstrual irregularities such as amenorrhoea, oligomenorrhea and suppression of ovulation, pregnancy is not uncommon.
Hansson, Robert C +3 more
core +1 more source